Publications 2019
227) Adipocyte metabolism is improved by TNF receptor-targeting small RNAs identified from dried nuts. Aquilano K, Ceci V, Gismondi A, De Stefano S, Iacovelli F, Faraonio R, Di Marco G, Poerio N, Minutolo A, Minopoli G, Marcone A, Fraziano M, Tortolici F, Sennato S, Casciardi S, Potestà M, Bernardini R, Mattei M, Falconi M, Montesano C, Rufini S, Canini A, Lettieri-Barbato D. Commun Biol. 2019 Aug 21;2(1):317. doi: 10.1038/s42003-019-0563-7.
226) Constitutive alterations in vesicular trafficking increase the sensitivity of cells from celiac disease patients to gliadin. Lania G, Nanayakkara M, Maglio M, Auricchio R, Porpora M, Conte M, De Matteis MA, Rizzo R, Luini A, Discepolo V, Troncone R, Auricchio S, Barone MV. Commun Biol. 2019 May 20;2(1):190. doi: 10.1038/s42003-019-0443-1.
225) Fyn Kinase Is Involved in EPO Receptor Signaling and Is Required to Harmonize the Response to Oxidation. Beneduce E, Mattè A, De Falco L, Cedrick S, Tolosano E, Chiabrando D, Siciliano A, Iolascon A, Narla M, De Franceschi L. Blood. 2017 Dec 7;130(Suppl_1):9. doi: 10.1182/blood.V130.Suppl_1.9.9.
224) Transdifferentiation of Mouse Embryonic Fibroblasts into Dopaminergic Neurons Reactivates LINE-1 Repetitive Elements. Della Valle F, Thimma MP, Caiazzo M, Pulcrano S, Celii M, Adroub SA, Liu P, Alanis-Lobato G, Broccoli V, Orlando V. Stem Cell Reports. 2019 Dec 21. pii: S2213-6711(19)30416-3. doi: 10.1016/j.stemcr.2019.12.002. [Epub ahead of print]
223) Setup of Quantitative PCR for Oral Neisseria spp. Evaluation in Celiac Disease Diagnosis. Esposito MV, Nardelli C, Granata I, Pagliuca C, D'Argenio V, Russo I, Guarracino MR, Salvatore P, Del Vecchio Blanco G, Ciacci C, Sacchetti L. Diagnostics (Basel). 2019 Dec 26;10(1). pii: E12. doi: 10.3390/diagnostics10010012.
222) Familial hypercholesterolemia: A complex genetic disease with variable phenotypes. Di Taranto MD, Giacobbe C, Fortunato G. Eur J Med Genet. 2019 Dec 25:103831. doi: 10.1016/j.ejmg.2019.103831. [Epub ahead of print] Review.
221) Chemical Composition of Aspergillus creber Extract and Evaluation of its Antimicrobial and Antioxidant Activities. Sakhri A, Chaouche NK, Catania MR, Ritieni A, Santini A. Pol J Microbiol. 2019 Sep;68(3):309-316. doi: 10.33073/pjm-2019-033. Epub 2019 Sep 3.
220) Gene Copy Number and Post-Transductional Mechanisms Regulate TRAP1 Expression in Human Colorectal Carcinomas. Pietrafesa M, Maddalena F, Possidente L, Condelli V, Zoppoli P, Li Bergolis V, Rodriquenz MG, Aieta M, Vita G, Esposito F, Landriscina M. Int J Mol Sci. 2019 Dec 24;21(1). pii: E145. doi: 10.3390/ijms21010145.
219) Prenatal Diagnosis of Cystic Fibrosis and Hemophilia: Incidental Findings and Weak Points. Comegna M, Maruotti GM, Sarno L, Cernera G, Gelzo M, Guida M, Zullo F, Zarrilli F, Castaldo G. Diagnostics (Basel). 2019 Dec 21;10(1). pii: E7. doi: 10.3390/diagnostics10010007.
218) A case of Cerebrotendinous Xanthomatosis with spinal cord involvement and without tendon xanthomas: identification of a new mutation of the CYP27A1 gene. Gelzo M, Di Taranto MD, Bisecco A, D'Amico A, Capuano R, Giacobbe C, Caputo M, Cirillo M, Tedeschi G, Fortunato G, Corso G. Acta Neurol Belg. 2019 Dec 24. doi: 10.1007/s13760-019-01267-4. [Epub ahead of print]
217) Design and application of oncolytic viruses for cancer immunotherapy. Ylösmäki E, Cerullo V. Curr Opin Biotechnol. 2019 Dec 21;65:25-36. doi: 10.1016/j.copbio.2019.11.016. [Epub ahead of print] Review.
216) NOX2-Dependent Reactive Oxygen Species Regulate Formyl-Peptide Receptor 1-Mediated TrkA Transactivation in SH-SY5Y Cells. Castaldo M, Zollo C, Esposito G, Ammendola R, Cattaneo F. Oxid Med Cell Longev. 2019 Dec 2;2019:2051235. doi: 10.1155/2019/2051235. eCollection 2019.
215) Insight into Nephrocan Function in Mouse Endoderm Patterning. Addeo M, Buonaiuto S, Guerriero I, Amendola E, Visconte F, Marino A, De Angelis MT, Russo F, Roberto L, Marotta P, Russo NA, Iervolino A, Amodio F, De Felice M, Lucci V, Falco G.Int J Mol Sci. 2019 Dec 18;21(1). pii: E8. doi: 10.3390/ijms21010008.
214) PAX8 expression in high-grade serous ovarian cancer positively regulates attachment to ECM via Integrin β3. Soriano AA, de Cristofaro T, Di Palma T, Dotolo S, Gokulnath P, Izzo A, Calì G, Facchiano A, Zannini M. Cancer Cell Int. 2019 Nov 20;19:303. doi: 10.1186/s12935-019-1022-8. eCollection 2019.
213) Artificially cloaked viral nanovaccine for cancer immunotherapy. Fusciello M, Fontana F, Tähtinen S, Capasso C, Feola S, Martins B, Chiaro J, Peltonen K, Ylösmäki L, Ylösmäki E, Hamdan F, Kari OK, Ndika J, Alenius H, Urtti A, Hirvonen JT, Santos HA, Cerullo V. Nat Commun. 2019 Dec 17;10(1):5747. doi: 10.1038/s41467-019-13744-8.
212) Emerging drugs in randomized controlled trials for sickle cell disease: are we on the brink of a new era in research and treatment? Matte A, Cappellini MD, Iolascon A, Enrica F, De Franceschi L. Expert Opin Investig Drugs. 2019 Dec 17. doi: 10.1080/13543784.2020.1703947. [Epub ahead of print]
211) A Novel εγδβ-Thalassemia Deletion Associated with Severe Anemia at Birth and a β-Thalassemia Intermedia Phenotype Later in Life in Three Generations of a Greek Family. Makis A, Georgiou I, Traeger-Synodinos J, Storino MR, Giuliano M, Andolfo I, Hatzimichael E, Chaliasos N, Giapros V, Izzo P, Iolascon A, Grosso M. Hemoglobin. 2019 Dec 12:1-4. doi: 10.1080/03630269.2019.1699568. [Epub ahead of print]
210) TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKKβ/VPS34 pathway. Scotto Rosato A, Montefusco S, Soldati C, Di Paola S, Capuozzo A, Monfregola J, Polishchuk E, Amabile A, Grimm C, Lombardo A, De Matteis MA, Ballabio A, Medina DL. Nat Commun. 2019 Dec 10;10(1):5630. doi: 10.1038/s41467-019-13572-w.
209) Childhood obesity: an overview of laboratory medicine, exercise and microbiome. Scudiero O, Pero R, Ranieri A, Terracciano D, Fimiani F, Cesaro A, Gentile L, Leggiero E, Laneri S, Moscarella E, Mazzaccara C, Frisso G, D'Alicandro G, Limongelli G, Pastore L, Calabrò P, Lombardo B. Clin Chem Lab Med. 2019 Dec 10. pii: /j/cclm.ahead-of-print/cclm-2019-0789/cclm-2019-0789.xml. doi: 10.1515/cclm-2019-0789. [Epub ahead of print] Review.
208) Metabolic Alterations in Cardiomyocytes of Patients with Duchenne and Becker Muscular Dystrophies. Esposito G, Carsana A. J Clin Med. 2019 Dec 5;8(12). pii: E2151. doi: 10.3390/jcm8122151. Review.
207) Promising Colorectal Cancer Biomarkers for Precision Prevention and Therapy. Turano M, Delrio P, Rega D, Cammarota F, Polverino A, Duraturo F, Izzo P, De Rosa M. Cancers (Basel). 2019 Dec 4;11(12). pii: E1932. doi: 10.3390/cancers11121932. Review
206) Heat shock proteins in thyroid malignancies: Potential therapeutic targets for poorly-differentiated and anaplastic tumours? Lettini G, Pietrafesa M, Lepore S, Maddalena F, Crispo F, Sgambato A, Esposito F, Landriscina M. Mol Cell Endocrinol. 2019 Dec 5:110676. doi: 10.1016/j.mce.2019.110676. [Epub ahead of print] Review.
205) Phosphoproteomic analysis sheds light on intracellular signaling cascades triggered by Formyl-Peptide Receptor 2. Cattaneo F, Russo R, Castaldo M, Chambery A, Zollo C, Esposito G, Pedone PV, Ammendola R. Sci Rep. 2019 Nov 29;9(1):17894. doi: 10.1038/s41598-019-54502-6.
204) A novel decalin-based bicyclic scaffold for FKBP51-selective ligands. Feng X, Sippel C, Knaup F, Bracher A, Staibano S, Romano MF, Hausch F. J Med Chem. 2019 Dec 4. doi: 10.1021/acs.jmedchem.9b01157. [Epub ahead of print]
203) Hsp70s transcription-translation relationship depends on the heat shock temperature in zebrafish. Mottola G, Nikinmaa M, Anttila K. Comp Biochem Physiol A Mol Integr Physiol. 2019 Nov 29:110629. doi: 10.1016/j.cbpa.2019.110629. [Epub ahead of print]
202) Mitochondrial mass governs the extent of human T cell senescence. Callender LA, Carroll EC, Bober EA, Akbar AN, Solito E, Henson SM. Aging Cell. 2019 Dec 2:e13067. doi: 10.1111/acel.13067. [Epub ahead of print]
201) Transcription factors involved in tumorigenesis are over-represented in mutated active DNA binding sites in neuroblastoma. Capasso M, Lasorsa VA, Cimmino F, Avitabile M, Cantalupo S, Montella A, De Angelis B, Morini M, de Torres C, Castellano A, Locatelli F, Iolascon A. Cancer Res. 2019 Nov 29. pii: canres.2883.2019. doi: 10.1158/0008-5472.CAN-19-2883. [Epub ahead of print]
200) Thyroid hormone induces progression and invasiveness of squamous cell carcinomas by promoting a ZEB-1/E-cadherin switch. Miro C, Di Cicco E, Ambrosio R, Mancino G, Di Girolamo D, Cicatiello AG, Sagliocchi S, Nappi A, De Stefano MA, Luongo C, Antonini D, Visconte F, Varricchio S, Ilardi G, Del Vecchio L, Staibano S, Boelen A, Blanpain C, Missero C, Salvatore D, Dentice M. Nat Commun. 2019 Nov 27;10(1):5410. doi: 10.1038/s41467-019-13140-2.
199) Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery. Pagliuca C, Scaglione E, Carraturo F, Mantova G, Marino MM, Pishbin MV, Pagliarulo C, Colicchio R, Salvatore P. J Vis Exp. 2019 Nov 5;(153). doi: 10.3791/60047.
198) Cytofluorimetric and immunohistochemical comparison for detecting bone marrow infiltration in non-Hodgkin lymphomas: a study of 354 patients. Statuto T, Valvano L, Calice G, Villani O, Pietrantuono G, Mansueto G, D'Arena G, Vita G, Lalinga V, Possidente L, Del Vecchio L, D'Auria F, Musto P.Leuk Res. 2019 Nov 12;88:106267. doi: 10.1016/j.leukres.2019.106267. [Epub ahead of print]
197) Genomic co-amplification of CDK4/MDM2/FRS2 is associated with very poor prognosis and atypical clinical features in neuroblastoma patients. Amoroso L, Ognibene M, Morini M, Conte M, Di Cataldo A, Tondo A, D'Angelo P, Castellano A, Garaventa A, Lasorsa VA, Podestà M, Capasso M, Pezzolo A. Genes Chromosomes Cancer.2019 Nov 22.doi: 10.1002/gcc.22827. [Epub ahead of print]
196) Gain-of-function mutations in PIEZO1 directly impair hepatic iron metabolism via the inhibition of the BMP/SMADs pathway. Andolfo I, Rosato BE, Manna F, De Rosa G, Marra R, Gambale A, Girelli D, Russo R, Iolascon A. Am J Hematol. 2019 Nov 18. doi: 10.1002/ajh.25683. [Epub ahead of print]
195) Circulating microRNAs as biomarkers for early diagnosis of cutaneous melanoma. Carpi S, Polini B, Fogli S, Podestà A, Ylösmäki E, Cerullo V, Romanini A, Nieri P. Expert Rev Mol Diagn. 2019 Nov 20. doi: 10.1080/14737159.2020.1696194. [Epub ahead of print]
194) Development of a Stromal Microenvironment Experimental Model Containing Proto-Myofibroblast Like Cells and Analysis of Its Crosstalk with Melanoma Cells: A New Tool to Potentiate and Stabilize Tumor Suppressor Phenotype of Dermal Myofibroblasts. Avagliano A, Ruocco MR, Nasso R, Aliotta F, Sanità G, Iaccarino A, Bellevicine C, Calì G, Fiume G, Masone S, Masullo M, Montagnani S, Arcucci A. Cells. 2019 Nov 14;8(11). pii: E1435. doi: 10.3390/cells8111435.
193) Unconventional secretion of α-Crystallin B requires the Autophagic pathway and is controlled by phosphorylation of its serine 59 residue. D'Agostino M, Scerra G, Cannata Serio M, Caporaso MG, Bonatti S, Renna M. Sci Rep. 2019 Nov 15;9(1):16892. doi: 10.1038/s41598-019-53226-x.
192) Selective demethylation of two CpG sites causes postnatal activation of the Dao gene and consequent removal of D-serine within the mouse cerebellum. Cuomo M, Keller S, Punzo D, Nuzzo T, Affinito O, Coretti L, Carella M, de Rosa V, Florio E, Boscia F, Avvedimento VE, Cocozza S, Errico F, Usiello A, Chiariotti L. Clin Epigenetics. 2019 Oct 28;11(1):149. doi: 10.1186/s13148-019-0732-z.
191) EHA Research Roadmap on Hemoglobinopathies and Thalassemia: An Update. Iolascon A, De Franceschi L, Muckenthaler M, Taher A, Rees D, de Montalembert M, Rivella S, Eleftheriou A, Cappellini MD. Hemasphere. 2019 Jun 4;3(3):e208. doi: 10.1097/HS9.0000000000000208. eCollection 2019 Jun. Review.
190) Increased frequency of regulatory T cells in pediatric inflammatory bowel disease at diagnosis: a compensative role? Vitale A, Strisciuglio C, Vitale S, Santopaolo M, Bruzzese D, Micillo T, Scarpato E, Miele E, Staiano A, Troncone R, Matarese G, Gianfrani C. Pediatr Res. 2019 Nov 12. doi: 10.1038/s41390-019-0662-7. [Epub ahead of print]
189) Identification and Characterization of Nasal Polyposis and Mycoplasma Superinfection by Scanning Electron Microscopy and Nasal Cytology with Optical Microscopy: A Case Report. Caruso AA, Viola V, Del Prete S, Leo S, Marasco D, Fulgione A, Naviglio D, Gallo M. Diagnostics (Basel). 2019 Nov 4;9(4). pii: E174. doi: 10.3390/diagnostics9040174.
188) Integrating Medical Humanities into medical school training. Bifulco M, Pisanti S. EMBO Rep. 2019 Oct 30:e48830. doi: 10.15252/embr.201948830. [Epub ahead of print]
187) Hypermethioninemia in Campania: Results from 10 years of newborn screening. Villani GRD, Albano L, Caterino M, Crisci D, Di Tommaso S, Fecarotta S, Fisco MG, Frisso G, Gallo G, Mazzaccara C, Marchese E, Nolano A, Parenti G, Pecce R, Redi A, Salvatore F, Strisciuglio P, Turturo MG, Vallone F, Ruoppolo M. Mol Genet Metab Rep. 2019 Oct 11;21:100520. doi: 10.1016/j.ymgmr.2019.100520. eCollection 2019 Dec.
186) Harnessing therapeutic viruses as a delivery vehicle for RNA-based therapy. Ylösmäki L, Polini B, Carpi S, Martins B, Smertina E, Feola S, Fusciello M, Peltonen K, Nieri P, Ylösmäki E, Cerullo V. PLoS One. 2019 Oct 23;14(10):e0224072. doi: 10.1371/journal.pone.0224072. eCollection 2019.
185) Potential and Challenges of Aptamers as Specific Carriers of Therapeutic Oligonucleotides for Precision Medicine in Cancer. Nuzzo S, Roscigno G, Affinito A, Ingenito F, Quintavalle C, Condorelli G. Cancers (Basel). 2019 Oct 10;11(10). pii: E1521. doi: 10.3390/cancers11101521. Review.
184) Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition). Cossarizza A, […], Matarese G, […], Zychlinsky A. Eur J Immunol. 2019 Oct;49(10):1457-1973. doi: 10.1002/eji.201970107.
183) First trimester ultrasound features of X-linked Opitz syndrome and early molecular diagnosis: case report and review of the literature. Sarno L, Maruotti GM, Izzo A, Mazzaccara C, Carbone L, Esposito G, Di Cresce M, Saccone G, Sirico A, Genesio R, Mollo N, Martinelli P, Conti A, Zullo F, Frisso G. J Matern Fetal Neonatal Med. 2019 Oct 21:1-5. doi: 10.1080/14767058.2019.1677594. [Epub ahead of print]
182) The Wnt/Ca2+ pathway is involved in interneuronal communication mediated by tunneling nanotubes. Vargas JY, Loria F, Wu YJ, Córdova G, Nonaka T, Bellow S, Syan S, Hasegawa M, van Woerden GM, Trollet C, Zurzolo C. EMBO J. 2019 Oct 18:e101230. doi: 10.15252/embj.2018101230. [Epub ahead of print]
181) Exploring the Molecular Crosstalk between Pancreatic Bud and Mesenchyme in Embryogenesis: Novel Signals Involved. Guerriero I, De Angelis MT, D'Angelo F, Leveque R, Savignano E, Roberto L, Lucci V, Mazzone P, Laurino S, Storto G, Nardelli A, Sgambato A, Ceccarelli M, De Felice M, Amendola E, Falco G. Int J Mol Sci. 2019 Oct 3;20(19). pii: E4900. doi: 10.3390/ijms20194900.
180)Neural crest-derived tumor neuroblastoma and melanoma share 1p13.2 as susceptibility locus that shows a long-range interaction with the SLC16A1 gene. Avitabile M, Succoio M, Testori A, Cardinale A, Vaksman Z, Lasorsa VA, Cantalupo S, Esposito M, Cimmino F, Montella A, Formicola D, Koster J, Andreotti V, Ghiorzo P, Romano MF, Staibano S, Scalvenzi M, Ayala F, Hakonarson H, Corrias MV, Devoto M, Law MH, Iles MM, Brown K, Diskin S, Zambrano N, Iolascon A, Capasso M. Carcinogenesis. 2019 Sep 7. pii: bgz153. doi: 10.1093/carcin/bgz153. [Epub ahead of print]
179) The GR-ANXA1 pathway is a pathological player and a candidate target in epilepsy. Zub E, Canet G, Garbelli R, Blaquiere M, Rossini L, Pastori C, Sheikh M, Reutelingsperger C, Klement W, de Bock F, Audinat E, Givalois L, Solito E, Marchi N. FASEB J. 2019 Oct 16:fj201901596R. doi: 10.1096/fj.201901596R. [Epub ahead of print]
178) PATZ1 Is Overexpressed in Pediatric Glial Tumors and Correlates with Worse Event-Free Survival in High-grade Gliomas. Passariello A, Errico ME, Donofrio V, Maestrini M, Zerbato A, Cerchia L, Capasso M, Capasso M, Fedele M. Cancers (Basel). 2019 Oct 11;11(10). pii: E1537. doi: 10.3390/cancers11101537.
177) A Phospholipid Profile at 4 Months Predicts the Onset of Celiac Disease in at-Risk Infants. Auricchio R, Galatola M, Cielo D, Amoresano A, Caterino M, De Vita E, Illiano A, Troncone R, Greco L, Ruoppolo M. Sci Rep. 2019 Oct 4;9(1):14303. doi: 10.1038/s41598-019-50735-7.
176) Bitopertin, a selective oral GLYT1 inhibitor, improves anemia in a mouse model of beta-thalassemia. Matte A, Federti E, Winter M, Koerner A, Harmeier A, Mazer N, Tomka T, Di Paolo ML, De Falco L, Andolfo I, Beneduce E, Iolascon A, Macias-Garcia A, Chen JJ, Janin A, Leboeuf C, Turrini F, Brugnara C, De Franceschi L. JCI Insight. 2019 Oct 8. pii: 130111. doi: 10.1172/jci.insight.130111. [Epub ahead of print]
175) Hematopoietic Stem Cell Transplantation in Congenital Dyserythropetic Anemia Type II: A Case Report and Review of the Literature. Uygun V, Russo R, Karasu G, Daloğlu H, Iolascon A, Yeşilipek A. J Pediatr Hematol Oncol. 2019 Oct 4. doi: 10.1097/MPH.0000000000001612. [Epub ahead of print]
174) Daily Fructose Traces Intake and Liver Injury in Children with Hereditary Fructose Intolerance. Di Dato F, Spadarella S, Puoti MG, Caprio MG, Pagliardini S, Zuppaldi C, Vallone G, Fecarotta S, Esposito G, Iorio R, Parenti G, Spagnuolo MI. Nutrients. 2019 Oct 7;11(10). pii: E2397. doi: 10.3390/nu11102397.
173) The splicing FK506-binding protein-51 isoform plays a role in glioblastoma resistance through programmed cell death ligand-1 expression regulation. D'Arrigo P, Digregorio M, Romano S, Tufano M, Rea A, Hausch F, Dedobbeleer M, Vigorito V, Russo S, Bauder M, Rogister B, Romano MF. Cell Death Discov. 2019 Sep 24;5:137. doi: 10.1038/s41420-019-0216-0. eCollection 2019.
172) Adiponectin Expression Is Modulated by Long-Term Physical Activity in Adult Patients Affected by Cystic Fibrosis. Polito R, Nigro E, Elce A, Monaco ML, Iacotucci P, Carnovale V, Comegna M, Gelzo M, Zarrilli F, Corso G, Castaldo G, Daniele A. Mediators Inflamm. 2019 Sep 9;2019:2153934. doi: 10.1155/2019/2153934. eCollection 2019.
171) Double knock-out of Hmga1 and Hipk2 genes causes perinatal death associated to respiratory distress and thyroid abnormalities in mice. Gerlini R, Amendola E, Conte A, Valente V, Tornincasa M, Credendino SC, Cammarota F, Gentile C, Di Guida L, Paladino S, De Vita G, Fusco A, Pierantoni GM. Cell Death Dis. 2019 Oct 3;10(10):747. doi: 10.1038/s41419-019-1975-5.
170) A ceRNA circuitry involving the long noncoding RNA Klhl14-AS, Pax8 and Bcl2 drives thyroid carcinogenesis. Credendino SC, Bellone ML, Lewin N, Amendola E, Sanges R, Basu S, Sepe R, Decaussin-Petrucci M, Tinto N, Fusco A, De Felice M, De Vita G. Cancer Res. 2019 Sep 26. pii: canres.0039.2019. doi: 10.1158/0008-5472.CAN-19-0039. [Epub ahead of print]
169) CoDysAn: A Telemedicine Tool to Improve Awareness and Diagnosis for Patients With Congenital Dyserythropoietic Anemia. Tornador C, Sánchez-Prados E, Cadenas B, Russo R, Venturi V, Andolfo I, Hernández-Rodriguez I, Iolascon A, Sánchez M. Front Physiol. 2019 Sep 13;10:1063. doi: 10.3389/fphys.2019.01063. eCollection 2019.
168) Sample Size for Oxidative Stress and Inflammation When Treating Multiple Sclerosis with Interferon-β1a and Coenzyme Q10. Moccia M, Capacchione A, Lanzillo R, Carbone F, Micillo T, Matarese G, Palladino R, Brescia Morra V. Brain Sci. 2019 Sep 27;9(10). pii: E259. doi: 10.3390/brainsci9100259.
167) N6-Isopentenyladenosine Inhibits Colorectal Cancer and Improves Sensitivity to 5-Fluorouracil-Targeting FBXW7 Tumor Suppressor. Fiore D, Piscopo C, Proto MC, Vasaturo M, Dal Piaz F, Fusco BM, Pagano C, Laezza C, Bifulco M, Gazzerro P. Cancers (Basel). 2019 Sep 28;11(10). pii: E1456. doi: 10.3390/cancers11101456.
166) A Functional Analysis of the Unclassified Pro2767Ser BRCA2 Variant Reveals Its Potential Pathogenicity that Acts by Hampering DNA Binding and Homology-Mediated DNA Repair. Esposito MV, Minopoli G, Esposito L, D'Argenio V, Di Maggio F, Sasso E, D'Aiuto M, Zambrano N, Salvatore F. Cancers (Basel). 2019 Sep 28;11(10). pii: E1454. doi: 10.3390/cancers11101454.
165) The Discovery of RNA Aptamers that Selectively Bind Glioblastoma Stem Cells. Affinito A, Quintavalle C, Esposito CL, Roscigno G, Vilardo C, Nuzzo S, Vitiani LR, De Luca G, Pallini R, Kichkailo AS, Lapin IN, de Franciscis V, Condorelli G. Mol Ther Nucleic Acids. 2019 Aug 22;18:99-109. doi: 10.1016/j.omtn.2019.08.015. [Epub ahead of print]
164) Metabolism and Autoimmune Responses: The microRNA Connection. Colamatteo A, Micillo T, Bruzzaniti S, Fusco C, Garavelli S, De Rosa V, Galgani M, Spagnuolo MI, Di Rella F, Puca AA, de Candia P, Matarese G. Front Immunol. 2019 Aug 28;10:1969. doi: 10.3389/fimmu.2019.01969. eCollection 2019. Review.
163) Microbiome Influence in the Pathogenesis of Prion and Alzheimer's Diseases. D'Argenio V, Sarnataro D. Int J Mol Sci. 2019 Sep 23;20(19). pii: E4704. doi: 10.3390/ijms20194704. Review.
162) The Role of Exo-miRNAs in Cancer: A Focus on Therapeutic and Diagnostic Applications. Ingenito F, Roscigno G, Affinito A, Nuzzo S, Scognamiglio I, Quintavalle C, Condorelli G. Int J Mol Sci. 2019 Sep 21;20(19). pii: E4687. doi: 10.3390/ijms20194687. Review.
161) HMGA and Cancer: A Review on Patent Literatures. De Martino M, Fusco A, Esposito F. Recent Pat Anticancer Drug Discov. 2019 Sep 19. doi: 10.2174/1574892814666190919152001. [Epub ahead of print]
160) Novel Human Anti-PD-L1 mAbsInhibit Immune-IndependentTumor Cell Growth and PD-L1 AssociatedIntracellularSignalling. Passariello M, D'Alise AM, Esposito A, Vetrei C, Froechlich G, Scarselli E, Nicosia A, De Lorenzo C. Sci Rep. 2019 Sep 11;9(1):13125. doi: 10.1038/s41598-019-49485-3.
159) Beta-defensins and analogs in Helicobacterpyloriinfections: mRNAexpressionlevels, DNA methylation, and antibacterialactivity. Pero R, Angrisano T, Brancaccio M, Falanga A, Lombardi L, Natale F, Laneri S, Lombardo B, Galdiero S, Scudiero O. PLoSOne. 2019 Sep 19;14(9):e0222295. doi: 10.1371/journal.pone.0222295. eCollection 2019
158) The Arg499His gain-of-functionmutation in the C-terminal domain of PCSK9. Sánchez-Hernández RM, Di Taranto MD, Benito-Vicente A, Uribe KB, Lamiquiz-Moneo I, Larrea-Sebal A, Jebari S, Galicia-Garcia U, Nóvoa FJ, Boronat M, Wägner AM, Civeira F, Martín C, Fortunato G. Atherosclerosis. 2019 Aug 30;289:162-172. doi: 10.1016/j.atherosclerosis.2019.08.020. [Epubahead of print]
157) Crosstalk between 14-3-3θ and AF4 enhances MLL-AF4 activity and promotes leukemia cell proliferation. Fioretti T, Cevenini A, Zanobio M, Raia M, Sarnataro D, Salvatore F, Esposito G. Cell Oncol (Dordr). 2019 Sep 6. doi: 10.1007/s13402-019-00468-6. [Epub ahead of print]
156) GKN1 expression in gastric cancer cells is negatively regulated by miR-544a. Stella di Stadio C, Faraonio R, Federico A, Altieri F, Rippa E, Arcari P. Biochimie. 2019 Sep 8. pii: S0300-9084(19)30263-9. doi: 10.1016/j.biochi.2019.09.005. [Epub ahead of print]
155) Insights into Thymus Development and Viral Thymic Infections. Albano F, Vecchio E, Renna M, Iaccino E, Mimmi S, Caiazza C, Arcucci A, Avagliano A, Pagliara V, Donato G, Palmieri C, Mallardo M, Quinto I, Fiume G. Viruses. 2019 Sep 9;11(9). pii: E836. doi: 10.3390/v11090836. Review.
154) The Golgi complex: 120 years and it doesn't show. De Matteis MA, Corda D, Luini A. FEBS Lett. 2019 Sep;593(17):2277-2279. doi: 10.1002/1873-3468.13577. No abstract available.
153) Gut microbiome investigation in celiac disease: from methods to its pathogenetic role. Sacchetti L, Nardelli C. Clin Chem Lab Med. 2019 Sep 9. pii: /j/cclm.ahead-of-print/cclm-2019-0657/cclm-2019-0657.xml. doi: 10.1515/cclm-2019-0657. [Epub ahead of print] Review.
152) Human NPCs can degrade α-syn fibrils and transfer them preferentially in a cell contact-dependent manner possibly through TNT-like structures. Grudina C, Kouroupi G, Nonaka T, Hasegawa M, Matsas R, Zurzolo C. Neurobiol Dis. 2019 Sep 5:104609. doi: 10.1016/j.nbd.2019.104609. [Epub ahead of print]
151) Emerging Role of USP8, HMGA, and Non-Coding RNAs in Pituitary Tumorigenesis. D'Angelo D, De Martino M, Arra C, Fusco A. Cancers (Basel). 2019 Sep 4;11(9). pii: E1302. doi: 10.3390/cancers11091302. Review.
150) Novel Human Bispecific Aptamer-Antibody Conjugates for Efficient Cancer Cell Killing. Passariello M, Camorani S, Vetrei C, Cerchia L, De Lorenzo C. Cancers (Basel). 2019 Aug 29;11(9). pii: E1268. doi: 10.3390/cancers11091268.
149)Exploring Shared Susceptibility between Two Neural Crest Cells Originating Conditions: Neuroblastoma and Congenital Heart Disease. Testori A, Lasorsa VA, Cimmino F, Cantalupo S, Cardinale A, Avitabile M, Limongelli G, Russo MG, Diskin S, Maris J, Devoto M, Keavney B, Cordell HJ, Iolascon A, Capasso M. Genes (Basel). 2019 Aug 30;10(9). pii: E663. doi: 10.3390/genes10090663.
148) Control of expression and activity of peroxisome proliferated-activated receptor γ by Annexin A1 on microglia during efferocytosis. da Rocha GHO, Loiola RA, Pantaleão LDN, Reutelingsperger C, Solito E, Farsky SHP. Cell BiochemFunct. 2019 Sep 3. doi: 10.1002/cbf.3433. [Epub ahead of print]
147) Heparan sulfate proteoglycans: The sweet side of development turns sour in mucopolysaccharidoses. De Pasquale V, Pavone LM. BiochimBiophys Acta Mol Basis Dis. 2019 Aug 26:165539. doi: 10.1016/j.bbadis.2019.165539. [Epub ahead of print] Review.
146) Reduced Annexin A1 Expression Associates with Disease Severity and Inflammation in Multiple Sclerosis Patients. Colamatteo A, Maggioli E, AzevedoLoiola R, Hamid Sheikh M, Calì G, Bruzzese D, Maniscalco GT, Centonze D, Buttari F, Lanzillo R, Perna F, Zuccarelli B, Mottola M, Cassano S, Galgani M, Solito E, De Rosa V. J Immunol. 2019 Aug 28. pii: ji1801683. doi: 10.4049/jimmunol.1801683. [Epub ahead of print] Front Immunol. 2019 Aug 13;10:1908. doi: 10.3389/fimmu.2019.01908. eCollection 2019.
145) Adipocyte metabolism is improved by TNF receptor-targeting small RNAs identified from dried nuts. Aquilano K, Ceci V, Gismondi A, De Stefano S, Iacovelli F, Faraonio R, Di Marco G, Poerio N, Minutolo A, Minopoli G, Marcone A, Fraziano M, Tortolici F, Sennato S, Casciardi S, Potestà M, Bernardini R, Mattei M, Falconi M, Montesano C, Rufini S, Canini A, Lettieri-Barbato D. Commun Biol. 2019 Aug 21;2:317. doi: 10.1038/s42003-019-0563-7. eCollection 2019.
144) The Sweet Kiss Breaching Immunological Self-Tolerance. Galgani M, Matarese G. Trends Mol Med. 2019 Aug 22. pii: S1471-4914(19)30211-4. doi: 10.1016/j.molmed.2019.08.003. [Epub ahead of print]
143) Ageritin from poplar mushrooms: scale-up purification and cytotoxicity towards undifferentiated and differentiated SH-SY5Y cells. Ragucci S, Pacifico S, Ruocco MR, Crescente G, Nasso R, Simonetti M, Masullo M, Piccolella S, Pedone PV, Landi N, Di Maro A. Food Funct. 2019 Aug 23. doi: 10.1039/c9fo01483g. [Epub ahead of print]
142) Cystic Fibrosis: The Sense of Smell. Di Lullo AM, Iacotucci P, Comegna M, Amato F, Dolce P, Castaldo G, Cantone E, Carnovale V, Iengo M. Am J Rhinol Allergy. 2019 Aug 20:1945892419870450. doi: 10.1177/1945892419870450. [Epub ahead of print] No abstract available.
141) The TRAPP complex mediates secretion arrest induced by stress granule assembly. Zappa F, Wilson C, Di Tullio G, Santoro M, Pucci P, Monti M, D'Amico D, Pisonero-Vaquero S, De Cegli R, Romano A, Saleem MA, Polishchuk E, Failli M, Giaquinto L, De Matteis MA. EMBO J. 2019 Aug20:e101704. doi: 10.15252/embj.2019101704. [Epub ahead of print]
140) New Linear Precursors of cIDPR Derivatives as Stable Analogs of cADPR: A Potent Second Messenger with Ca2+-Modulating Activity Isolated from Sea Urchin Eggs. D'Errico S, Basso E, Falanga AP, Marzano M, Pozzan T, Piccialli V, Piccialli G, Oliviero G, Borbone N. Mar Drugs. 2019 Aug 17;17(8). pii: E476. doi: 10.3390/md17080476.
139) Cell stemness, epithelial-to-mesenchymal transition, and immunoevasion: Intertwined aspects in cancer metastasis. Romano S, Tufano M, D'Arrigo P, Vigorito V, Russo S, Romano MF. Semin Cancer Biol. 2019 Aug 15. pii: S1044-579X(19)30052-5. doi: 10.1016/j.semcancer.2019.08.015. [Epub ahead of print] Review.
138) The evolving role of genetic tests in reproductive medicine. Cariati F, D'Argenio V, Tomaiuolo R. J Transl Med. 2019 Aug 14;17(1):267. doi: 10.1186/s12967-019-2019-8. Review.
137) Novel variants of unknown significance in the PMS2 gene identified in patients with hereditary colon cancer. Liccardo R, Della Ragione C, Mitilini N, De Rosa M, Izzo P, Duraturo F. Cancer Manag Res. 2019 Jul 18;11:6719-6725. doi: 10.2147/CMAR.S167348. eCollection 2019.
136) Clustering in the Golgi apparatus governs sorting and function of GPI-APs in polarized epithelial cells. Lebreton S, Paladino S, Zurzolo C. FEBS Lett. 2019 Aug 10. doi: 10.1002/1873-3468.13573. [Epub ahead of print] Review.
135) The BMP-SMAD pathway mediates the impaired hepatic iron metabolism associated with the ERFE-A260S variant. Andolfo I, Rosato BE, Marra R, De Rosa G, Manna F, Gambale A, Iolascon A, Russo R. Am J Hematol. 2019 Aug 10. doi: 10.1002/ajh.25613. [Epub ahead of print]
134) Endovascular Treatment Versus Medical Therapy for Hypertensive Patients with Renal Artery Stenosis: An Updated Systematic Review. Piaggio D, Bracale U, Pecchia L, Di Taranto MD, Sodo M, Bracale UM. Ann Vasc Surg. 2019 Jul 31. pii: S0890-5096(19)30506-0. doi: 10.1016/j.avsg.2019.04.050. [Epub ahead of print] Review.
133) The best of both worlds- bringing together cell biology and infection at the Institut Pasteur. Zurzolo C, Enninga J. MicrobesInfect. 2019 Jul 30. pii: S1286-4579(19)30074-7. doi: 10.1016/j.micinf.2019.06.014. [Epub ahead of print]
132) Tamoxifen erythroid toxicity revealed by studying the role of nuclear receptor co-activator 4 in erythropoiesis. Nai A, Pettinato M, Federico G, Olivari V, Carlomagno F, Silvestri L. Haematologica. 2019 Aug;104(8):e383-e384. doi: 10.3324/haematol.2019.224857. No abstract available.
131) Metabolic Dysregulations and Epigenetics: A Bidirectional Interplay that Drives Tumor Progression. Crispo F, Condelli V, Lepore S, Notarangelo T, Sgambato A, Esposito F, Maddalena F, Landriscina M. Cells. 2019 Jul 30;8(8). pii: E798. doi: 10.3390/cells8080798. Review.
130)Advances in understanding the pathogenesis of red cell membrane disorders. Iolascon A, Andolfo I, Russo R. Br J Haematol. 2019 Jul 31. doi: 10.1111/bjh.16126. [Epub ahead of print] Review.
129) Metabolic flexibility in melanoma: A potential therapeutic target. Ruocco MR, Avagliano A, Granato G, Vigliar E, Masone S, Montagnani S, Arcucci A. Semin Cancer Biol. 2019 Jul 27. pii: S1044-579X(19)30004-5. doi: 10.1016/j.semcancer.2019.07.016. [Epub ahead of print] Review.
128) Health tourism: an opportunity for sustainable development. Illario M, De Luca V, Leonardini L, Kucharczyk M, Parent AS, Dantas C, Jegundo AL, van Staalduinen W, Ganzarain J, Comisso L, Bramezza C, Carriazo AM, Maritati A, Tramontano G, Capozzi P, Goossens E, Cotrone C, Costantini A, Ciliberti M, Femiano M, d'Amore A, Forlenza M, Ruggiero R, Bianchi A, Augustin L, Marrazzo V, Dello Ioio T, Capaldo S, Crudeli A, De Cesare G, Cuccaro F, Bracale G, Tramontano D, Postiglione A, Matera C, Coscioni E, Bousquet J. Transl Med UniSa. 2019 Jan 6;19:109-115. eCollection 2019 Jan-Jun.
127) Hormonal control of trained immunity: aldosterone at the crossroad between activation of innate immunity and cardiovascular diseases. Matarese G, Norata GD. Cardiovasc Res. 2019 Jul 25. pii: cvz191. doi: 10.1093/cvr/cvz191. [Epubahead of print] No abstractavailable.
126) Pioglitazone Improves Mitochondrial Organization and Bioenergetics in Down Syndrome Cells. Mollo N, Nitti M, Zerillo L, Faicchia D, Micillo T, Accarino R, Secondo A, Petrozziello T, Calì G, Cicatiello R, Bonfiglio F, Sarnataro V, Genesio R, Izzo A, Pinton P, Matarese G, Paladino S, Conti A, Nitsch L. Front Genet. 2019 Jun 28;10:606. doi: 10.3389/fgene.2019.00606. eCollection 2019.
125) Type 2 Diabetes: How Much of an Autoimmune Disease? de Candia P, Prattichizzo F, Garavelli S, De Rosa V, Galgani M, Di Rella F, Spagnuolo MI, Colamatteo A, Fusco C, Micillo T, Bruzzaniti S, Ceriello A, Puca AA, Matarese G. Front Endocrinol (Lausanne). 2019 Jul 4;10:451. doi: 10.3389/fendo.2019.00451. eCollection 2019.
124) The Molecular Hallmarks of the Serrated Pathway in Colorectal Cancer. De Palma FDE, D'Argenio V, Pol J, Kroemer G, Maiuri MC, Salvatore F. Cancers (Basel). 2019 Jul 20;11(7). pii: E1017. doi: 10.3390/cancers11071017. Review.
123) Heat shock proteins in cancer stem cell maintenance: A potential therapeutic target? Lettini G, Lepore S, Crispo F, Sisinni L, Esposito F, Landriscina M. Histol Histopathol. 2019 Jul 19:18153. doi: 10.14670/HH-18-153. [Epub ahead of print]
122) PERK-Mediated Unfolded Protein Response Activation and Oxidative Stress in PARK20 Fibroblasts. Amodio G, Moltedo O, Fasano D, Zerillo L, Oliveti M, Di Pietro P, Faraonio R, Barone P, Pellecchia MT, De Rosa A, De Michele G, Polishchuk E, Polishchuk R, Bonifati V, Nitsch L, Pierantoni GM, Renna M, Criscuolo C, Paladino S, Remondelli P. Front Neurosci. 2019 Jun 27;13:673. doi: 10.3389/fnins.2019.00673. eCollection 2019.
121) An immunometabolic pathomechanism for chronic obstructive pulmonary disease. Bruzzaniti S, Bocchino M, Santopaolo M, Calì G, Stanziola AA, D'Amato M, Esposito A, Barra E, Garziano F, Micillo T, Zuchegna C, Romano A, De Simone S, Zuccarelli B, Mottola M, De Rosa V, Porcellini A, Perna F, Matarese G, Galgani M. Proc Natl Acad Sci U S A. 2019 Jul 15. pii: 201906303. doi: 10.1073/pnas.1906303116. [Epub ahead of print]
120) Prevalence and clinical significance of red flags in patients with hypertrophic cardiomyopathy. Limongelli G, Monda E, Tramonte S, Gragnano F, Masarone D, Frisso G, Esposito A, Gravino R, Ammendola E, Salerno G, Rubino M, Caiazza M, Russo M, Calabrò P, Elliott PM, Pacileo G. Int J Cardiol. 2019 Jul 4. pii: S0167-5273(19)30883-6. doi: 10.1016/j.ijcard.2019.06.073. [Epub ahead of print]
119) Estrogen Promotes Pro-resolving Microglial Behavior and Phagocytic Cell Clearance Through the Actions of Annexin A1. Loiola RA, Wickstead ES, Solito E, McArthur S. Front Endocrinol (Lausanne). 2019 Jun 26;10:420. doi: 10.3389/fendo.2019.00420. eCollection 2019.
118) Discovery of Novel Naphthylphenylketone and Naphthylphenylamine Derivatives as Cell Division Cycle 25B (CDC25B) Phosphatase Inhibitors: Design, Synthesis, Inhibition Mechanism and in Vitro Efficacy against Melanoma Cell Lines. Cerchia C, Nasso R, Mori M, Villa S, Gelain A, Capasso A, Aliotta F, Simonetti M, Rullo R, Masullo M, De Vendittis E, Ruocco MR, Lavecchia A. J Med Chem. 2019 Jul 11. doi: 10.1021/acs.jmedchem.9b00632. fundas samsung galaxy j5 [Epub ahead of print]
117) Oncolytic adenovirus drives specific immune response generated by a poly-epitope pDNA vaccine encoding melanoma neoantigens into the tumor site. Lopes A, Feola S, Ligot S, Fusciello M, Vandermeulen G, Préat V, Cerullo V. J Immunother Cancer. 2019 Jul 10;7(1):174. doi: 10.1186/s40425-019-0644-7.
116) Germline mutations and new copy number variants among 40 pediatric cancer patients suspected for genetic predisposition. Gambale A, Russo R, Andolfo I, Quaglietta L, De Rosa G, Contestabile V, De Martino L, Genesio R, Pignataro P, Giglio S, Capasso M, Parasole R, Pasini B, Iolascon A. Clin Genet. 2019 Jul 6. doi: 10.1111/cge.13600. [Epub ahead of print]
115) Rapid Solid-Liquid Dynamic Extraction (RSLDE): A Powerful and Greener Alternative to the Latest Solid-Liquid Extraction Techniques. Naviglio D, Scarano P, Ciaravolo M, Gallo M. Foods. 2019 Jul 5;8(7). pii: E245. doi: 10.3390/foods8070245. Review.
114) HUVEC Tube-formation Assay to Evaluate the Impact of Natural Products on Angiogenesis. Gentile MT, Pastorino O, Bifulco M, Colucci-D'Amato L. J Vis Exp. 2019 Jun 24;(148). doi: 10.3791/58591.
113) Proteomics and metabolomics studies exploring the pathophysiology of renal dysfunction in autosomal dominant polycystic kidney disease and other ciliopathies. Zacchia M, Marchese E, Trani EM, Caterino M, Capolongo G, Perna A, Ruoppolo M, Capasso G. Nephrol Dial Transplant. 2019 Jun 20. pii: gfz121. doi: 10.1093/ndt/gfz121. [Epub ahead of print]
112) Vitamin D Status in Paget Disease of Bone and Efficacy-Safety Profile of Cholecalciferol Treatment in Pagetic Patients with Hypovitaminosis D. Rendina D, De Filippo G, Merlotti D, Di Stefano M, Succoio M, Muggianu SM, Bianciardi S, D'Elia L, Coppo E, Faraonio R, Nuti R, Strazzullo P, Gennari L. Calcif Tissue Int. 2019 Jun 24. doi: 10.1007/s00223-019-00578-1. [Epub ahead of print]
111) Adenoviral vaccine targeting multiple neoantigens as strategy to eradicate large tumors combined with checkpoint blockade. D'Alise AM, Leoni G, Cotugno G, Troise F, Langone F, Fichera I, De Lucia M, Avalle L, Vitale R, Leuzzi A, Bignone V, Di Matteo E, Tucci FG, Poli V, Lahm A, Catanese MT, Folgori A, Colloca S, Nicosia A, Scarselli E. Nat Commun. 2019 Jun 19;10(1):2688. doi: 10.1038/s41467-019-10594-2.
110) A Novel View of Human Helicobacter pylori Infections: Interplay between Microbiota and Beta-Defensins. Pero R, Brancaccio M, Laneri S, Biasi MG, Lombardo B, Scudiero O. Biomolecules. 2019 Jun 18;9(6). pii: E237. doi: 10.3390/biom9060237. Review.
109) Feedback inhibition of cAMP effector signaling by a chaperone-assisted ubiquitin system. Rinaldi L, Delle Donne R, Catalanotti B, Torres-Quesada O, Enzler F, Moraca F, Nisticò R, Chiuso F, Piccinin S, Bachmann V, Lindner HH, Garbi C, Scorziello A, Russo NA, Synofzik M, Stelzl U, Annunziato L, Stefan E, Feliciello A. Nat Commun. 2019 Jun 12;10(1):2572. doi: 10.1038/s41467-019-10037-y.
108) Porous Silicon-Based Aptasensors: The Next Generation of Label-Free Devices for Health Monitoring. Terracciano M, Rea I, Borbone N, Moretta R, Oliviero G, Piccialli G, De Stefano L. Molecules. 2019 Jun 13;24(12). pii: E2216. doi: 10.3390/molecules24122216. Review.
107) Wee1 Rather Than Plk1 Is Inhibited by AZD1775 at Therapeutically Relevant Concentrations. Serpico AF, D'Alterio G, Vetrei C, Della Monica R, Nardella L, Visconti R, Grieco D. Cancers (Basel). 2019 Jun 13;11(6). pii: E819. doi: 10.3390/cancers11060819.
106) Characterization of Two Cases of Congenital Dyserythropoietic Anemia Type I Shed Light on the Uncharacterized C15orf41 Protein. Russo R, Marra R, Andolfo I, De Rosa G, Rosato BE, Manna F, Gambale A, Raia M, Unal S, Barella S, Iolascon A. Front Physiol. 2019 May 22;10:621. doi: 10.3389/fphys.2019.00621. eCollection 2019.
105) Biodistribution and sensitive tracking of immune cells with plasmonic gold nanostars. Liu Y, Huang W, Xiong C, Huang Y, Chen BJ, Racioppi L, Chao N, Vo-Dinh T. Int J Nanomedicine. 2019 May 9;14:3403-3411. doi: 10.2147/IJN.S192189. eCollection 2019.
104) The Metallophosphoesterase-Domain-Containing Protein 2 (MPPED2) Gene Acts as Tumor Suppressor in Breast Cancer. Pellecchia S, Sepe R, Federico A, Cuomo M, Credendino SC, Pisapia P, Bellevicine C, Nicolau-Neto P, Severo Ramundo M, Crescenzi E, De Vita G, Terracciano LM, Chiariotti L, Fusco A, Pallante P. Cancers (Basel). 2019 Jun 8;11(6). pii: E797. doi: 10.3390/cancers11060797.
103) Molecular diagnosis of MODY3 permitted to reveal a de novo 12q24.31 deletion and to explain a complex phenotype in a young diabetic patient. Iafusco F, De Sanctis P, Pirozzi D, Capone S, Lombardo B, Gambale A, Confetto S, Zanfardino A, Iolascon A, Pastore L, Iafusco D, Tinto N. Clin Chem Lab Med. 2019 Jun 11. pii: /j/cclm.ahead-of-print/cclm-2019-0137/cclm-2019-0137.xml. doi: 10.1515/cclm-2019-0137. [Epub ahead of print] No abstract available.
102) A novel member of Prame family, Gm12794c, counteracts retinoic acid differentiation through the methyltransferase activity of PRC2. Napolitano G, Tagliaferri D, Fusco S, Cirillo C, De Martino I, Addeo M, Mazzone P, Russo NA, Natale F, Cardoso MC, De Luca L, Lamorte D, La Rocca F, De Felice M, Falco G. Cell Death Differ. 2019 Jun 11. doi: 10.1038/s41418-019-0359-9. [Epub ahead of print]
101) AXL Is a Novel Predictive Factor and Therapeutic Target for Radioactive Iodine Refractory Thyroid Cancer. Collina F, La Sala L, Liotti F, Prevete N, La Mantia E, Chiofalo MG, Aquino G, Arenare L, Cantile M, Liguori G, Di Gennaro F, Pezzullo L, Losito NS, Vecchio G, Botti G, Melillo RM, Franco R. Cancers (Basel). 2019 Jun 7;11(6). pii: E785. doi: 10.3390/cancers11060785.
100)Tbx1 regulates extracellular matrix-cell interactions in the second heart field. Alfano D, Altomonte A, Cortes C, Bilio M, Kelly RG, Baldini A. Hum Mol Genet. 2019 Apr 1. pii: ddz058. doi: 10.1093/hmg/ddz058. [Epub ahead of print]
99) Wound healing activity and phytochemical screening of purified fractions of Sempervivum tectorum L. leaves on HCT 116. Cattaneo F, De Marino S, Parisi M, Festa C, Castaldo M, Finamore C, Duraturo F, Zollo C, Ammendola R, Zollo F, Iorizzi M. Phytochem Anal. 2019 Jun 5. doi: 10.1002/pca.2844. [Epub ahead of print]
98) Effects of Long-Term Citrate Treatment in the PC3 Prostate Cancer Cell Line. Caiazza C, D'Agostino M, Passaro F, Faicchia D, Mallardo M, Paladino S, Pierantoni GM, Tramontano D. Int J Mol Sci. 2019 May 28;20(11). pii: E2613. doi: 10.3390/ijms20112613.
97) RYR1 Sequence Variants in Myopathies: Expression and Functional Studies in Two Families. Zullo A, Perrotta G, D'Angelo R, Ruggiero L, Gravino E, Del Vecchio L, Santoro L, Salvatore F, Carsana A. Biomed Res Int. 2019 Apr 21;2019:7638946. doi: 10.1155/2019/7638946. eCollection 2019.
96) CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer. Racioppi L, Nelson ER, Huang W, Mukherjee D, Lawrence SA, Lento W, Masci AM, Jiao Y, Park S, York B, Liu Y, Baek AE, Drewry DH, Zuercher WJ, Bertani FR, Businaro L, Geradts J, Hall A, Means AR, Chao N, Chang CY, McDonnell DP. Nat Commun. 2019 Jun 4;10(1):2450. doi: 10.1038/s41467-019-10424-5.
95) HSP90 Molecular Chaperones, Metabolic Rewiring, and Epigenetics: Impact on Tumor Progression and Perspective for Anticancer Therapy. Condelli V, Crispo F, Pietrafesa M, Lettini G, Matassa DS, Esposito F, Landriscina M, Maddalena F. Cells. 2019 Jun 3;8(6). pii: E532. doi: 10.3390/cells8060532. fundas huawei p8 lite 2017 Review.
94) Obesity worsens central inflammation and disability in multiple sclerosis. Stampanoni Bassi M, Iezzi E, Buttari F, Gilio L, Simonelli I, Carbone F, Micillo T, De Rosa V, Sica F, Furlan R, Finardi A, Fantozzi R, Storto M, Bellantonio P, Pirollo P, Di Lemme S, Musella A, Mandolesi G, Centonze D, Matarese G. Mult Scler. 2019 Jun 4:1352458519853473. doi: 10.1177/1352458519853473. [Epub ahead of print]
93) Cardiotoxicity and pro-inflammatory effects of the immune checkpoint inhibitor Pembrolizumab associated to Trastuzumab. Quagliariello V, Passariello M, Coppola C, Rea D, Barbieri A, Scherillo M, Monti MG, Iaffaioli RV, De Laurentiis M, Ascierto PA, Botti G, De Lorenzo C, Maurea N. Int J Cardiol. 2019 May 17. pii: S0167-5273(18)37531-4. doi: 10.1016/j.ijcard.2019.05.028. [Epub ahead of print]
92) The thyroid hormone activating enzyme, type 2 deiodinase, induces myogenic differentiation by regulating mitochondrial metabolism and reducing oxidative stress. Sagliocchi S, Cicatiello AG, Di Cicco E, Ambrosio R, Miro C, Di Girolamo D, Nappi A, Mancino G, De Stefano MA, Luongo C, Raia M, Ogawa-Wong AN, Zavacki AM, Paladino S, Salvatore D, Dentice M. Redox Biol. 2019 May 22;24:101228. doi: 10.1016/j.redox.2019.101228. [Epub ahead of print]
91) Microdeletion of pseudogene chr14.232.a affects LRFN5 expression in cells of a patient with autism spectrum disorder. Cappuccio G, Attanasio S, Alagia M, Mutarelli M, Borzone R, Karali M, Genesio R, Mormile A, Nitsch L, Imperati F, Esposito A, Banfi S, Del Giudice E, Brunetti-Pierri N. Eur J Hum Genet. 2019 May 31. doi: 10.1038/s41431-019-0430-5. [Epub ahead of print]
90) Silver-nanoparticles as plasmon-resonant enhancers for eumelanin's photoacoustic signal in a self-structured hybrid nanoprobe. Silvestri B, Armanetti P, Sanità G, Vitiello G, Lamberti A, Calì G, Pezzella A, Luciani G, Menichetti L, Luin S, d'Ischia M. Mater Sci Eng C Mater Biol Appl. 2019 Sep;102:788-797. doi: 10.1016/j.msec.2019.04.066. Epub 2019 Apr 30.
89) Novel role for cannabidiol in circadian clock function. Bifulco M, Navarra G, Laezza C, Pagano C. Addict Biol. 2019 May 27:e12772. doi: 10.1111/adb.12772. [Epub ahead of print] No abstract available.
88) Constitutive alterations in vesicular trafficking increase the sensitivity of cells from celiac disease patients to gliadin. Lania G, Nanayakkara M, Maglio M, Auricchio R, Porpora M, Conte M, De Matteis MA, Rizzo R, Luini A, Discepolo V, Troncone R, Auricchio S, Barone MV. Commun Biol. 2019 May 20;2:190. doi: 10.1038/s42003-019-0443-1. eCollection 2019.
87) HMGA1 negatively regulates NUMB expression at transcriptional and post transcriptionallevel in glioblastoma stem cells. Puca F, Tosti N, Federico A, Kuzay Y, Pepe A, Morlando S, Savarese T, D'Alessio F, Colamaio M, Sarnataro D, Ziberi S, De Martino M, Fusco A, Battista S. Cell Cycle. 2019 May 22:1-12. doi: 10.1080/15384101.2019.1618541. [Epub ahead of print]
86) Annexin-A1: Therapeutic Potential in Microvascular Disease. Purvis GSD, Solito E, Thiemermann C. Front Immunol. 2019 Apr 30;10:938. doi: 10.3389/fimmu.2019.00938. eCollection 2019. Review.
85) DNA methylation dynamic of bone marrow hematopoietic stem cells after allogeneic transplantation. Trino S, Zoppoli P, Carella AM, Laurenzana I, Weisz A, Memoli D, Calice G, La Rocca F, Simeon V, Savino L, Del Vecchio L, Musto P, Caivano A, De Luca L. Stem Cell Res Ther. 2019 May 20;10(1):138. doi: 10.1186/s13287-019-1245-6.
84) Editorial. Mallardo M, Poltronieri P, Farooqi AA. Semin Cancer Biol. 2019 May 15. pii: S1044-579X(19)30136-1. doi: 10.1016/j.semcancer.2019.05.008. [Epub ahead of print] No abstract available.
83) Biohybrid Vaccines for Improved Treatment of Aggressive Melanoma with Checkpoint Inhibitor. Fontana F, Fusciello M, Groeneveldt C, Capasso C, Chiaro J, Feola S, Liu Z, Mäkilä EM, Salonen JJ, Hirvonen JT, Cerullo V, Santos HA. ACS Nano. 2019 May 17. doi: 10.1021/acsnano.8b09613. [Epub ahead of print]
82) Overexpression of HMGA1 Figures as a Potential Prognostic Factor in EndometrioidEndometrial Carcinoma (EEC). Palumbo Júnior A, de Sousa VPL, Esposito F, De Martino M, Forzati F, Moreira FCB, Simão TA, Nasciutti LE, Fusco A, Ribeiro Pinto LF, Bessa Pereira Chaves C, Meireles Da Costa N. Genes (Basel). 2019 May 15;10(5). pii: E372. doi: 10.3390/genes10050372.
81) Nucleotide distance influences co-methylation between nearby CpG sites. Affinito O, Palumbo D, Fierro A, Cuomo M, De Riso G, Monticelli A, Miele G, Chiariotti L, Cocozza S. Genomics. 2019 May 10. pii: S0888-7543(19)30017-5. doi: 10.1016/j.ygeno.2019.05.007. [Epub ahead of print]
80) Intein-mediated protein trans-splicing expands adeno-associated virus transfer capacity in the retina. Tornabene P, Trapani I, Minopoli R, Centrulo M, Lupo M, de Simone S, Tiberi P, Dell'Aquila F, Marrocco E, Iodice C, Iuliano A, Gesualdo C, Rossi S, Giaquinto L, Albert S, Hoyng CB, Polishchuk E, Cremers FPM, Surace EM, Simonelli F, De Matteis MA, Polishchuk R, Auricchio A. Sci Transl Med. 2019 May 15;11(492). pii: eaav4523. doi: 10.1126/scitranslmed.aav4523.
79) Erythrocyte ion content and dehydration modulate maximal Gardos channel activity in KCNN4V282M/+ Hereditary Xerocytosis (HX) red cells. Rivera A, Vandorpe DH, Shmukler BE, Andolfo I, Iolascon A, Archer NM, Shabani E, Auerbach M, Hamerschlak N, Morton J, Wohlgemuth JG, Brugnara C, Snyder LM, Alper SL. Am J Physiol Cell Physiol. 2019 May 15. doi: 10.1152/ajpcell.00074.2019. [Epub ahead of print]
78) Highly Homogeneous Biotinylated Carbon Nanodots: Red-emitting Nano-heaters as Theranostic Agents Towards Precision Cancer Medicine. Scialabba C, Sciortino A, Messina F, Buscarino G, Cannas M, Roscigno G, Condorelli G, Cavallaro G, Giammona G, Mauro N. ACS Appl Mater Interfaces. 2019 May 15. doi: 10.1021/acsami.9b04925. [Epub ahead of print]
77) Preclinical toxicology and safety pharmacology of the first-in-class GADD45β/MKK7 inhibitor andclinical candidate, DTP3. Tornatore L, Capece D, D'Andrea D, Begalli F, Verzella D, Bennett J, Acton G, Campbell EA, Kelly J, Tarbit M, Adams N, Bannoo S, Leonardi A, Sandomenico A, Raimondo D, Ruvo M, Chambery A, Oblak M, Al-Obaidi MJ, Kaczmarski RS, Gabriel I, Oakervee HE, Kaiser MF, Wechalekar A, Benjamin R, Apperley JF, Auner HW, Franzoso G. Toxicol Rep. 2019 Apr 19;6:369-379. doi: 10.1016/j.toxrep.2019.04.006. eCollection 2019.
76) RPSAP52 lncRNA is overexpressed in pituitary tumors and promotes cell proliferation by acting as miRNA sponge for HMGA proteins. D'Angelo D, Mussnich P, Sepe R, Raia M, Del Vecchio L, Cappabianca P, Pellecchia S, Petrosino S, Saggio S, Solari D, Fraggetta F, Fusco A. J Mol Med (Berl). 2019 May 10. doi: 10.1007/s00109-019-01789-7. [Epub ahead of print]
75) GATA-1 isoforms differently contribute to the production and compartmentation of reactive oxygen species in the myeloid leukemia cell lineK562. Riccio P, Sessa R, de Nicola S, Petruzziello F, Trombetti S, Menna G, Pepe G, Maddalena P, Izzo P, Grosso M. J Cell Physiol. 2019 May 2. doi: 10.1002/jcp.28688. [Epubahead of print]
74) Intragenic Deletion in MACROD2: A Family with Complex Phenotypes Including Microcephaly, Intellectual Disability, Polydactyly, Renal and Pancreatic Malformations. Lombardo B, Esposito D, Iossa S, Vitale A, Verdesca F, Perrotta C, Di Leo L, Costa V, Pastore L, Franzé A. CytogenetGenome Res. 2019 May 3. doi: 10.1159/000499886. [Epubahead of print]
73) Mitochondrial Flexibility of Breast Cancers: A Growth Advantage and a Therapeutic Opportunity. Avagliano A, Ruocco MR, Aliotta F, Belviso I, Accurso A, Masone S, Montagnani S, Arcucci A. Cells. 2019 Apr 30;8(5). pii: E401. doi: 10.3390/cells8050401. Review.
72) Celiac disease-associated Neisseria flavescens decreases mitochondrial respiration in CaCo-2epithelial cells. Impact of Lactobacillus paracasei-CBA L74 on bacterial-induced cellular imbalance. Labruna G, Nanayakkara M, Pagliuca C, Nunziato M, Iaffaldano L, D'Argenio V, Colicchio R, Budelli AL, Nigro R, Salvatore P, Barone MV, Sacchetti L. Cell Microbiol. 2019 May 1:e13035. doi: 10.1111/cmi.13035. [Epub ahead of print]
71) Coffee prevents fatty liver disease induced by a high-fat diet by modulating pathways of the gut-liver axis. Vitaglione P, Mazzone G, Lembo V, D'Argenio G, Rossi A, Guido M, Savoia M, Salomone F, Mennella I, De Filippis F, Ercolini D, Caporaso N, Morisco F. J Nutr Sci. 2019 Apr 22;8:e15. doi: 10.1017/jns.2019.10. eCollection 2019.
70) Secondary metabolites produced by grapevine strains of Lasiodiplodia theobromae grown at two different temperatures. Félix C, Salvatore MM, DellaGreca M, Ferreira V, Duarte AS, Salvatore F, Naviglio D, Gallo M, Alves A, Esteves AC, Andolfi A. Mycologia. 2019 Apr 26:1-11. doi: 10.1080/00275514.2019.1600342. [Epub ahead of print]
69)Mathematical optimization of the green extraction of polyphenols from grape peels through a cyclic pressurization process. Gallo M, Formato A, Giacco R, Riccardi G, Lungo D, Formato G, Amoresano A, Naviglio D. Heliyon. 2019 Apr 17;5(4):e01526. doi: 10.1016/j.heliyon.2019.e01526. eCollection 2019 Apr.
68) Left pulmonary artery in 22q11.2 deletion syndrome. Echocardiographic evaluation in patients without cardiac defects and role of Tbx1 in mice. Mastromoro G, Calcagni G, Versacci P, Putotto C, Chinali M, Lambiase C, Unolt M, Pelliccione E, Anaclerio S, Caprio C, Cioffi S, Bilio M, Baban A, Drago F, Digilio MC, Marino B, Baldini A. PLoS One. 2019 Apr 1;14(4):e0211170. doi: 10.1371/journal.pone.0211170. eCollection 2019.
67) The best of both worlds-bringing together cell biology and infection at the Institut Pasteur. Zurzolo C, Enninga J. Genes Immun. 2019 Apr 25. doi: 10.1038/s41435-019-0068-x. [Epub ahead of print]
66) CHM/REP1 Transcript Expression and Loss of Visual Function in Patients Affected by Choroideremia. Di Iorio V, Esposito G, De Falco F, Boccia R, Fioretti T, Colucci R, De Rosa G, Melillo P, Salvatore F, Simonelli F, Testa F. Invest Ophthalmol Vis Sci. 2019 Apr 1;60(5):1547-1555. doi: 10.1167/iovs.18-25501.
65) Identification of AnnexinA1 as an Endogenous Regulator of RhoA, and Its Role in the Pathophysiology and Experimental Therapy of Type-2 Diabetes. Purvis GSD, Collino M, Loiola RA, Baragetti A, Chiazza F, Brovelli M, Sheikh MH, Collotta D, Cento A, Mastrocola R, Aragno M, Cutrin JC, Reutelingsperger C, Grigore L, Catapano AL, Yaqoob MM, Norata GD, Solito E, Thiemermann C. Front Immunol. 2019 Mar 27;10:571. doi: 10.3389/fimmu.2019.00571. eCollection 2019.
64) Pluripotent stem cell-derived bile canaliculi-forming hepatocytes to study genetic liver diseases involving hepatocyte polarity. Overeem AW, Klappe K, Parisi S, Klöters-Planchy P, Mataković L, du Teil Espina M, Drouin CA, Weiss KH, van IJzendoorn SCD. J Hepatol. 2019 Apr 6. pii: S0168-8278(19)30225-9. doi: 10.1016/j.jhep.2019.03.031. [Epub ahead of print]
63) The bifunctional protein GlmU is a key factor in biofilm formation induced by alkylating stress in Mycobacterium smegmatis. Di Somma A, Caterino M, Soni V, Agarwal M, di Pasquale P, Zanetti S, Molicotti P, Cannas S, Nandicoori VK, Duilio A. Res Microbiol. 2019 Apr 3. pii: S0923-2508(19)30034-8. doi: 10.1016/j.resmic.2019.03.002. [Epub ahead of print]
62)Effect of tolytoxin on tunneling nanotube formation and function. Dilsizoglu Senol A, Pepe A, Grudina C, Sassoon N, Reiko U, Bousset L, Melki R, Piel J, Gugger M, Zurzolo C. Sci Rep. 2019 Apr 5;9(1):5741. doi: 10.1038/s41598-019-42161-6.
61) Inhibition of lysine-specific demethylase LSD1 induces senescence in Glioblastoma cells through a HIF-1α-dependent pathway. Saccà CD, Gorini F, Ambrosio S, Amente S, Faicchia D, Matarese G, Lania L, Majello B. Biochim Biophys Acta Gene Regul Mech. 2019 Apr 2;1862(5):535-546. doi: 10.1016/j.bbagrm.2019.03.004. [Epub ahead of print]
60) PIEZO1 Hypomorphic Variants in Congenital Lymphatic Dysplasia Cause Shape and Hydration Alterations of Red Blood Cells. Andolfo I, De Rosa G, Errichiello E, Manna F, Rosato BE, Gambale A, Vetro A, Calcaterra V, Pelizzo G, De Franceschi L, Zuffardi O, Russo R, Iolascon A. Front Physiol. 2019 Mar 15;10:258. doi: 10.3389/fphys.2019.00258. eCollection 2019.
59) Lack of Rhes Increases MDMA-Induced Neuroinflammation and Dopamine Neuron Degeneration: Role of Gender and Age. Costa G, Porceddu PF, Serra M, Casu MA, Schiano V, Napolitano F, Pinna A, Usiello A, Morelli M. Int J Mol Sci. 2019 Mar 28;20(7). pii: E1556. doi: 10.3390/ijms20071556.
58) Helper-dependent adenovirus-mediated gene transfer of a secreted LDL receptor/transferrin chimeric protein reduces aortic atherosclerosis in LDL receptor-deficient mice. Leggiero E, Labruna G, Iaffaldano L, Lombardo B, Greco A, Fiorenza D, Gramanzini M, Montanaro D, Baldi A, Cerullo V, Sacchetti L, Pastore L. Gene Ther. 2019 Jan 30. doi: 10.1038/s41434-019-0061-z. [Epub ahead of print]
57) Features, reason for testing, and changes with time of 583 paroxysmal nocturnal hemoglobinuria clones from 529 patients: a multicenter Italian study. Cannizzo E, Raia M, De Propris MS, Triolo A, Scarpati B, Marfia A, Stacchini A, Buccisano F, Lanza F, Regazzoli A, Michelutti A, Cesaro S, Conte CA, Vanelli L, Tedone E, Omedè P, Ciriello MM, Caporale R, Catinella V, Pantano G, De Rosa C, Lo Pardo C, Poletti G, Ulbar F, Pavanelli MC, Del Pup L, Ottaviano V, Santonocito AM, Bartocci C, Boscaro E, Arras M, Amodeo R, Mestice A, Oliva B, Ferrari L, Statuto T, D'Auria F, Pianezze G, Tanca D, Visconte F, Rubba F, Musto P, Geuna M, Gatti A, Brando B, Del Vecchio L. Ann Hematol. 2019 Mar 13. doi: 10.1007/s00277-019-03644-8. [Epub ahead of print]
56) Coming together to define membrane contact sites. Scorrano L, De Matteis MA, Emr S, Giordano F, Hajnóczky G, Kornmann B, Lackner LL, Levine TP, Pellegrini L, Reinisch K, Rizzuto R, Simmen T, Stenmark H, Ungermann C, Schuldiner M. NatCommun. 2019 Mar 20;10(1):1287. doi: 10.1038/s41467-019-09253-3. Review.
55) Positive selection in Europeans and East-Asiansat the ABCA12 gene. Sirica R, Buonaiuto M, Petrella V, Sticco L, Tramontano D, Antonini D, Missero C, Guardiola O, Andolfi G, Kumar H, Ayub Q, Xue Y, Tyler-Smith C, Salvemini M, D'Angelo G, Colonna V. Sci Rep. 2019 Mar 19;9(1):4843. doi: 10.1038/s41598-019-40360-9.
54) Activation of NF-κB in B cell receptor signaling through Bruton'styrosinekinase-dependent phosphorylation of IκB-α. Pontoriero M, Fiume G, Vecchio E, de Laurentiis A, Albano F, Iaccino E, Mimmi S, Pisano A, Agosti V, Giovannone E, Altobelli A, Caiazza C, Mallardo M, Scala G, Quinto I. J MolMed (Berl). 2019 Mar 19. doi: 10.1007/s00109-019-01777-x. [Epubahead of print]
53) IncreasedRed Cell KCNN4 Activity in Sporadic Hereditary Xerocytosis Associated With Enhanced Single Channel Pressure Sensitivity of PIEZO1 Mutant V598M. Gnanasambandam R, Rivera A, Vandorpe DH, Shmukler BE, Brugnara C, Snyder LM, Andolfo I, Iolascon A, Silveira PA, Hamerschlak N, Gottlieb P, Alper SL. Hemasphere. 2018 Oct;2(5):e55. doi: 10.1097/HS9.0000000000000055. Epub 2018 Oct 2.
52) N-(1-carbamoyl-2-phenylethyl) butyramide reduces antibiotic-induced intestinalinjury, innate immune activation and modulates microbiota composition. Lama A, Annunziata C, Coretti L, Pirozzi C, Di Guida F, Nitrato Izzo A, Cristiano C, Mollica MP, Chiariotti L, Pelagalli A, Lembo F, Meli R, Mattace Raso G. Sci Rep. 2019 Mar 18;9(1):4832. doi: 10.1038/s41598-019-41295-x.
51) Iron and Ferritin Modulate MHC Class I Expression and NK Cell Recognition. Sottile R, Federico G, Garofalo C, Tallerico R, Faniello MC, Quaresima B, Cristiani CM, Di Sanzo M, Cuda G, Ventura V, Wagner AK, Contrò G, Perrotti N, Gulletta E, Ferrone S, Kärre K, Costanzo FS, Carlomagno F, Carbone E. Front Immunol. 2019 Feb 26;10:224. doi: 10.3389/fimmu.2019.00224. eCollection 2019.
50) Genetics, diagnosis and treatment of Lynch syndrome: Old lessons and current challenges. Duraturo F, Liccardo R, De Rosa M, Izzo P. Oncol Lett. 2019 Mar;17(3):3048-3054. doi: 10.3892/ol.2019.9945. Epub 2019 Jan 18. Review.
49)Expanding the Role of the Histone Lysine-Specific Demethylase LSD1 in Cancer. Majello B, Gorini F, Saccà CD, Amente S. Cancers (Basel). 2019 Mar 7;11(3). pii: E324. doi: 10.3390/cancers11030324. Review.
48) Glatiramer Acetate modulates ion channels expression and calcium homeostasis in B cell of patients with relapsing-remitting multiple sclerosis. Criscuolo C, Cianflone A, Lanzillo R, Carrella D, Carissimo A, Napolitano F, de Cegli R, de Candia P, La Rocca C, Petrozziello T, Matarese G, Boscia F, Secondo A, Di Bernardo D, Brescia Morra V. Sci Rep. 2019 Mar 12;9(1):4208. doi: 10.1038/s41598-018-38152-8.
47) Recent advances in understanding immune phenotypes of thyroid carcinomas: prognostication and emerging therapies. Liotti F, Prevete N, Vecchio G, Melillo RM. F1000Res. 2019 Feb 28;8. pii: F1000 Faculty Rev-227. doi: 10.12688/f1000research.16677.1. eCollection 2019. Review.
46) Two CFTR mutations within codon 970 differently impact on the chloride channel functionality. Amato F, Scudieri P, Musante I, Tomati V, Caci E, Comegna M, Maietta S, Manzoni F, di Lullo AM, De Wachter E, Vanderhelst E, Terlizzi V, Braggion C, Castaldo G, Galietta LJV. Hum Mutat. 2019 Mar 9. doi: 10.1002/humu.23741. [Epub ahead of print]
45) RNA Stabilizes Transcription-Dependent Chromatin Loops Induced By Nuclear Hormones. Pezone A, Zuchegna C, Tramontano A, Romano A, Russo G, de Rosa M, Vinciguerra M, Porcellini A, Gottesman ME, Avvedimento EV. Sci Rep. 2019 Mar 8;9(1):3925. doi: 10.1038/s41598-019-40123-6.
44) HIF-1 transcription activity: HIF1A driven response in normoxia and in hypoxia. Cimmino F, Avitabile M, Lasorsa VA, Montella A, Pezone L, Cantalupo S, Visconte F, Corrias MV, Iolascon A, Capasso M. BMC Med Genet. 2019 Feb 26;20(1):37. doi: 10.1186/s12881-019-0767-1.
43) Whole transcriptome targeted gene quantification provides new insights on pulmonary sarcomatoid carcinomas. Alì G, Bruno R, Poma AM, Affinito O, Monticelli A, Piaggi P, Ricciardi S, Lucchi M, Melfi F, Chella A, Cocozza S, Fontanini G. Sci Rep. 2019 Mar 5;9(1):3536. doi: 10.1038/s41598-019-40016-8.
42) Laboratory medicine: health evaluation in elite athletes. Lombardo B, Izzo V, Terracciano D, Ranieri A, Mazzaccara C, Fimiani F, Cesaro A, Gentile L, Leggiero E, Pero R, Izzo B, D'Alicandro AC, Ercolini D, D'Alicandro G, Frisso G, Pastore L, Calabrò P, Scudiero O. Clin Chem Lab Med. 2019 Mar 5. pii: /j/cclm.ahead-of-print/cclm-2018-1107/cclm-2018-1107.xml. doi: 10.1515/cclm-2018-1107. [Epub ahead of print] Review.
41) The complex CBX7-PRMT1 has a critical role in regulating E-cadherin gene expression and cell migration. Federico A, Sepe R, Cozzolino F, Piccolo C, Iannone C, Iacobucci I, Pucci P, Monti M, Fusco A. Biochim Biophys Acta Gene Regul Mech. 2019 Feb 28. pii: S1874-9399(18)30226-8. doi: 10.1016/j.bbagrm.2019.02.006. [Epub ahead of print]
40) Free d-aspartate triggers NMDA receptor-dependent cell death in primary cortical neurons and perturbs JNK activation, Tau phosphorylation, and protein SUMOylation in the cerebral cortex of mice lacking d-aspartate oxidase activity. Nuzzo T, Feligioni M, Cristino L, Pagano I, Marcelli S, Iannuzzi F, Imperatore R, D'Angelo L, Petrella C, Carella M, Pollegioni L, Sacchi S, Punzo D, De Girolamo P, Errico F, Canu N, Usiello A. Exp Neurol. fundas samsung galaxy s9 2019 Feb 26;317:51-65. doi: 10.1016/j.expneurol.2019.02.014. [Epub ahead of print]
39) Chromosomal Microarray Analysis versus Karyotyping in Fetuses with Increased Nuchal Translucency. Cicatiello R, Pignataro P, Izzo A, Mollo N, Pezone L, Maruotti GM, Sarno L, Sglavo G, Conti A, Genesio R, Nitsch L. Med Sci (Basel). 2019 Feb 27;7(3). pii: E40. doi: 10.3390/medsci7030040.
38) Coenzyme Q10 supplementation reduces peripheral oxidative stress and inflammation in interferon-β1a-treated multiple sclerosis. Moccia M, Capacchione A, Lanzillo R, Carbone F, Micillo T, Perna F, De Rosa A, Carotenuto A, Albero R, Matarese G, Palladino R, Brescia Morra V. Ther Adv Neurol Disord. 2019 Feb 18;12:1756286418819074. doi: 10.1177/1756286418819074. eCollection 2019.
37) Randomized controlled trial on the influence of dietary intervention on epigenetic mechanisms in children with cow's milk allergy: the EPICMA study. Paparo L, Nocerino R, Bruno C, Di Scala C, Cosenza L, Bedogni G, Di Costanzo M, Mennini M, D'Argenio V, Salvatore F, Berni Canani R. Sci Rep. 2019 Feb 26;9(1):2828. doi: 10.1038/s41598-019-38738-w.
36) Longitudinal transcriptomic and genetic landscape of radiotherapy response in canine melanoma. Giannuzzi D, Marconato L, Ramy E, Ferraresso S, Scarselli E, Fariselli P, Nicosia A, Pegolo S, Leoni G, Laganga P, Ferdinando LV, Giantin M, Troise F, Dacasto M, Aresu L. Vet Comp Oncol. 2019 Feb 25. doi: 10.1111/vco.12473. [Epub ahead of print]
35) Trotula de Ruggiero: The Magistra mulier sapiens and her medical dermatology treatises. Bifulco M, De Falco DD, Aquino RP, Pisanti S. J Cosmet Dermatol. 2019 Feb 25. doi: 10.1111/jocd.12882. [Epub ahead of print]
34) Dissecting Intra-Tumor Heterogeneity by the Analysis of Copy Number Variations in Single Cells: The Neuroblastoma Case Study. Cariati F, Borrillo F, Shankar V, Nunziato M, D'Argenio V, Tomaiuolo R. Int J Mol Sci. 2019 Feb 19;20(4). pii: E893. doi: 10.3390/ijms20040893.
33) Gene-environment interaction impacts on heart development and embryo survival. Moreau JLM, Kesteven S, Martin EMMA, Lau KS, Yam MX, O'Reilly VC, Del Monte-Nieto G, Baldini A, Feneley MP, Moon AM, Harvey RP, Sparrow DB, Chapman G, Dunwoodie SL. Development. 2019 Feb 20;146(4). pii: dev172957. doi: 10.1242/dev.172957.
32) Associationbetween DNA methylationprofile and malignancy in follicular-patternedthyroidneoplasms. Affinito O, Salerno P, D'Alessio AM, Cuomo M, Florio E, Carlomagno F, Proietti A, Giannini R, Basolo F, Chiariotti L, Cocozza S, Santoro M. EndocrRelatCancer. 2019 Feb 1. pii: ERC-18-0308.R2. doi: 10.1530/ERC-18-0308. [Epubahead of print]
31) Antimicrobial and anti-biofilm properties of novel synthetic lignan-like compounds. Vollaro A, Catania MR, Iesce MR, Sferruzza R, D'Abrosca B, Donnarumma G, De Filippis A, Cermola F, DellaGreca M, Buommino E. New Microbiol. 2019 Feb 20;42(1). [Epub ahead of print]
30) Endoplasmic Reticulum Stress and Unfolded Protein Response in Breast Cancer: The Balance between Apoptosis and Autophagy and Its Role in Drug Resistance. Sisinni L, Pietrafesa M, Lepore S, Maddalena F, Condelli V, Esposito F, Landriscina M. Int J Mol Sci. 2019 Feb 16;20(4). pii: E857. doi: 10.3390/ijms20040857. Review.
29) Unveiling Kiwifruit Metabolite and Protein Changes in the Course of Postharvest Cold Storage. Salzano AM, Renzone G, Sobolev AP, Carbone V, Petriccione M, Capitani D, Vitale M, Novi G, Zambrano N, Pasquariello MS, Mannina L, Scaloni A. Front Plant Sci. 2019 Feb 4;10:71. doi: 10.3389/fpls.2019.00071. eCollection 2019.
28) Brivanib in combination with Notch3 silencing shows potent activity in tumour models. Giovannini C, Salzano AM, Baglioni M, Vitale M, Scaloni A, Zambrano N, Giannone FA, Vasuri F, D'Errico A, Svegliati Baroni G, Bolondi L, Gramantieri L. Br J Cancer. 2019 Feb 15. doi: 10.1038/s41416-018-0375-4. [Epub ahead of print]
27) New G-Quadruplex-FormingOligodeoxynucleotidesIncorporating a Bifunctional Double-EndedLinker (DEL): Effects of DEL Size and ODNsOrientation on the Topology, Stability, and Molecularity of DEL-G-Quadruplexes. Marzano M, Falanga AP, D'Errico S, Pinto B, Roviello GN, Piccialli G, Oliviero G, Borbone N. Molecules. 2019 Feb 12;24(3). pii: E654. doi: 10.3390/molecules24030654.
26) Striatal spreading depolarization: Possibleimplication in levodopa-induceddyskinetic-likebehavior. de Iure A, Napolitano F, Beck G, QuirogaVarela A, Durante V, Sciaccaluga M, Mazzocchetti P, Megaro A, Tantucci M, Cardinale A, Punzo D, Mancini A, Costa C, Ghiglieri V, Tozzi A, Picconi B, Papa SM, Usiello A, Calabresi P. MovDisord. 2019 Feb 13. doi: 10.1002/mds.27632. [Epubahead of print]
25) Revealing membrane alteration in cellsoverexpressing CA IX and EGFR by Surface-EnhancedRamanScattering. Rusciano G, Sasso E, Capaccio A, Zambrano N, Sasso A. Sci Rep. 2019 Feb 12;9(1):1832. doi: 10.1038/s41598-018-37997-3
24) VAPB depletionaltersneuritogenesis and phosphoinositide balance in motoneuron-likecells: relevance to VAPB-linked ALS. Genevini P, Colombo MN, Venditti R, Marcuzzo S, Colombo SF, Bernasconi P, De Matteis MA, Borgese N, Navone F. J Cell Sci. 2019 Feb 11. pii: jcs.220061. doi: 10.1242/jcs.220061. [Epubahead of print]
23) Novelgenetically-modifiedchimpanzee adenovirus and MVA-vectoredrespiratorysyncytial virus vaccine safelyboostshumoral and cellularimmunity in healthyolderadults. Green CA, Sande CJ, Scarselli E, Capone S, Vitelli A, Nicosia A, Silva-Reyes L, Thompson AJ, de Lara CM, Taylor KS, Haworth K, Hutchings CL, Cargill T, Angus B, Klenerman P, Pollard AJ. J Infect. 2019 Feb 8. pii: S0163-4453(19)30038-6. doi: 10.1016/j.jinf.2019.02.003. [Epubahead of print]
22) PTX3: an inflammatoryproteinmodulatingultrastructure and bioenergetics of human endothelialcells. Carrizzo A, Procaccini C, Lenzi P, Fusco C, Villa F, Migliarino S, De Lucia M, Fornai F, Matarese G, Puca AA, Vecchione C. ImmunAgeing. 2019 Feb 2;16:4. doi: 10.1186/s12979-019-0144-0. eCollection 2019.
21) Lipidprofile and genetic status in a familialhypercholesterolemiapediatricpopulation: exploring the LDL/HDL ratio. Di Taranto MD, de Falco R, Guardamagna O, Massini G, Giacobbe C, Auricchio R, Malamisura B, Proto M, Palma D, Greco L, Fortunato G. ClinChem Lab Med. 2019 Feb 2. pii: /j/cclm.ahead-of-print/cclm-2018-1037/cclm-2018-1037.xml. doi: 10.1515/cclm-2018-1037. [Epubahead of print]
20) Virulence traits of serogroup C meningococcus and isogenic cssA mutant, defective in surface-exposedsialic acid, in a murine model of meningitis. Colicchio R, Pagliuca C, Ricci S, Scaglione E, Grandgirard D, Masouris I, Farina F, Pagliarulo C, Mantova G, Paragliola L, Leib SL, Koedel U, Pozzi G, Alifano P, Salvatore P. InfectImmun. 2019 Feb 4. pii: IAI.00688-18. doi: 10.1128/IAI.00688-18. [Epubahead of print]
19) A Novel Vaccine StrategyEmployingSerologicallyDifferentChimpanzeeAdenoviralVectors for the Prevention of HIV-1 and HCV Coinfection. Hartnell F, Brown A, Capone S, Kopycinski J, Bliss C, Makvandi-Nejad S, Swadling L, Ghaffari E, Cicconi P, Del Sorbo M, Sbrocchi R, Esposito I, Vassilev V, Marriott P, Gardiner CM, Bannan C, Bergin C, Hoffmann M, Turner B, Nicosia A, Folgori A, Hanke T, Barnes E, Dorrell L. Front Immunol. 2019 Jan 18;9:3175. doi: 10.3389/fimmu.2018.03175. eCollection 2018.
18) Optimization of EarlySteps in Oncolytic Adenovirus ONCOS-401 Production in T-175 and HYPERFlasks. Kuryk L, Møller AW, Vuolanto A, Pesonen S, Garofalo M, Cerullo V, Jaderberg M. Int J Mol Sci. 2019 Jan 31;20(3). pii: E621. doi: 10.3390/ijms20030621.
17) The transition from adolescence to adulthoodas a ‘sensitive period' for developingcancerrisk: the contribution of obesity and sociobehavioralmechanisms. Bifulco M, Abate M. Eur J CancerPrev. 2019 Mar;28(2):142. doi: 10.1097/CEJ.0000000000000425. No abstractavailable.
16) Molecular determinants of ER-Golgi contacts identified through a new FRET-FLIM system. Venditti R, Rega LR, Masone MC, Santoro M, Polishchuk E, Sarnataro D, Paladino S, D'Auria S, Varriale A, Olkkonen VM, Di Tullio G, Polishchuk R, De Matteis MA. J Cell Biol. 2019 Jan 18. pii: jcb.201812020. doi: 10.1083/jcb.201812020. [Epub ahead of print]
15) Contact-dependent growth inhibition systems in Acinetobacter. De Gregorio E, Zarrilli R, Di Nocera PP. Sci Rep. 2019 Jan 17;9(1):154. doi: 10.1038/s41598-018-36427-8.
14) Development of conformational antibodies targeting Cripto-1 with neutralizing effects in vitro. Focà G, Iaccarino E, Focà A, Sanguigno L, Untiveros G, Cuevas-Nunez M, Strizzi L, Leonardi A, Ruvo M, Sandomenico A. Biochimie. 2019 Jan 28. pii: S0300-9084(19)30024-0. doi: 10.1016/j.biochi.2019.01.016. [Epub ahead of print]
13) Helper-dependent adenovirus-mediated gene transfer of a secreted LDL receptor/transferrin chimeric protein reduces aortic atherosclerosis in LDL receptor-deficient mice. Leggiero E, Labruna G, Iaffaldano L, Lombardo B, Greco A, Fiorenza D, Gramanzini M, Montanaro D, Baldi A, Cerullo V, Sacchetti L, Pastore L. Gene Ther. 2019 Jan 30. doi: 10.1038/s41434-019-0061-z. [Epub ahead of print]
12) IFNβ enhances mesenchymal stromal (Stem) cells immunomodulatory function through STAT1-3 activation and mTOR-associated promotion of glucose metabolism. Vigo T, La Rocca C, Faicchia D, Procaccini C, Ruggieri M, Salvetti M, Centonze D, Matarese G, Uccelli A; MSRUN Network. Cell Death Dis. 2019 Jan 28;10(2):85. doi: 10.1038/s41419-019-1336-4.
11) The prion-like spreading of α-synuclein: From in vitro to in vivo models of Parkinson's disease. Vargas JY, Grudina C, Zurzolo C. Ageing Res Rev. 2019 Jan 25. pii: S1568-1637(18)30261-7. doi: 10.1016/j.arr.2019.01.012. [Epub ahead of print] Review.
10) Editorial: Novel Therapeutic Strategies for the Treatment of Chronic Diseases. Testa G, Passaro F, Cinquegrana A, Palma M, Abete P, Tocchetti CG. Curr Med Chem. 2019 Jan 28. doi: 10.2174/0929867325666190128121918. [Epub ahead of print]
9) Correlative cryo-electron microscopy reveals the structure of TNTs in neuronal cells. Sartori-Rupp A, Cordero Cervantes D, Pepe A, Gousset K, Delage E, Corroyer-Dulmont S, Schmitt C, Krijnse-Locker J, Zurzolo C. Nat Commun. 2019 Jan 21;10(1):342. doi: 10.1038/s41467-018-08178-7.
8) "Bisphenol a: an emerging threat to male fertility". Cariati F, D'Uonno N, Borrillo F, Iervolino S, Galdiero G, Tomaiuolo R. Reprod Biol Endocrinol. 2019 Jan 20;17(1):6. doi: 10.1186/s12958-018-0447-6. Review.
7) The activity of Sac1 across ER-TGN contact sites requires the four-phosphate-adaptor-protein-1. Venditti R, Masone MC, Rega LR, Di Tullio G, Santoro M, Polishchuk E, Serrano IC, Olkkonen VM, Harada A, Medina DL, La Montagna R, De Matteis MA. J Cell Biol. 2019 Jan 18. pii: jcb.201812021. doi: 10.1083/jcb.201812021. [Epub ahead of print]
6) Identification of a Novel Transcription Factor Required For Osteogenic Differentiation Of Mesenchymal Stem Cells. Querques F, D'Agostino A, Cozzolino C, Cozzuto L, Lombardo B, Leggiero E, Ruosi C, Pastore L. Stem Cells Dev. 2019 Jan 18. doi: 10.1089/scd.2018.0152. [Epub ahead of print]
5) A Toxicogenomic Approach Reveals a Novel Gene Regulatory Network Active in In Vitro and In Vivo Models of Thyroid Carcinogenesis. Reale C, Russo F, Credendino SC, Cuomo D, De Vita G, Mallardo M, Pennino F, Porreca I, Triassi M, De Felice M, Ambrosino C. Int J Environ Res Public Health. 2019 Jan 4;16(1). pii: E122. doi: 10.3390/ijerph16010122.
4) New Anti-Cancer Strategies in Testicular Germ Cell Tumors. Chieffi P, Martino MD, Esposito F. Recent Pat Anticancer Drug Discov. 2019 Jan 11. doi: 10.2174/1574892814666190111120023. [Epub ahead of print]
3) PNA-functionalized adenoviral vectors targeting G-quadruplexes in the P1 promoter of Bcl-2 proto-oncogene: a new tool for gene modulation in anti-cancer therapy. Falanga AP, Cerullo V, Marzano M, Feola S, Oliviero G, Piccialli G, Borbone N. Bioconjug Chem. 2019 Jan 8. doi: 10.1021/acs.bioconjchem.8b00674. [Epub ahead of print]
2) Biosensor for point-of-care analysis of immunoglobulins in urine by metal enhanced fluorescence from gold nanoparticles. Della Ventura B, Gelzo M, Battista E, Alabastri A, Schirato A, Castaldo G, Corso G, Gentile F, Velotta R. ACS Appl Mater Interfaces. 2019 Jan 4. doi: 10.1021/acsami.8b20501. [Epub ahead of print]
1) T-cell Activating Tribodies as a Novel Approach for Efficient Killing of ErbB2-positive Cancer Cells. Riccio G, Ricardo AR, Passariello M, Saraiva K, Rubino V, Cunnah P, Mertens N, De Lorenzo C. J Immunother. 2019 Jan;42(1):1-10.