Publications 2014
168) T cell activation induces CuZn superoxide dismutase (SOD)-1 intracellular re-localization, production and secretion.
Terrazzano G, Rubino V, Damiano S, Sasso A, Petrozziello T, Ucci V, Palatucci AT, Giovazzino A, Santillo M, De Felice B, Garbi C, Mondola P, Ruggiero G.
Biochim Biophys Acta. 2014 Feb;1843(2):265-74. doi: 10.1016/j.bbamcr.2013.10.020. Epub 2013 Oct 31.
167)The cl2/dro1/ccdc80 null mice develop thyroid and ovarian neoplasias.
Leone V, Ferraro A, Schepis F, Federico A, Sepe R, Arra C, Langella C, Palma G, De Lorenzo C, Troncone G, Masciullo V, Scambia G, Fusco A, Pallante P.
Cancer Lett. 2014 Dec 9. pii: S0304-3835(14)00753-8. doi: 10.1016/j.canlet.2014.12.010. [Epub ahead of print]
166) Inhibition of matrix metalloproteinases attenuates brain damage in experimental meningococcal meningitis.
Ricci S, Grandgirard D, Wenzel M, Braccini T, Salvatore P, Oggioni MR, Leib SL, Koedel U.
BMC Infect Dis. 2014 Dec 31;14(1):3853. [Epub ahead of print]
165) LENALIDOMIDE DIFFERENTLY MODULATES CD20 ANTIGEN SURFACE EXPRESSION ON CHRONIC LYMPHOCYTIC LEUKEMIA B-CELLS.
D’Arena G, Ruggieri V, D’Auria F, La Rocca F, Simeon V, Statuto T, Caivano A, Telesca D, Del Vecchio L, Musto P.
Leuk Lymphoma. 2014 Dec 30:1-8. [Epub ahead of print] No abstract available.
164) miR-23a, miR-24 and miR-27a protect differentiating ESCs from BMP4-induced apoptosis.
Musto A, Navarra A, Vocca A, Gargiulo A, Minopoli G, Romano S, Romano MF, Russo T, Parisi S.
Cell Death Differ. 2014 Dec 5. doi: 10.1038/cdd.2014.198. [Epub ahead of print]
163) A Phase Ia Study to Assess the Safety and Immunogenicity of New Malaria Vaccine Candidates ChAd63 CS Administered Alone and with MVA CS.
de Barra E, Hodgson SH, Ewer KJ, Bliss CM, Hennigan K, Collins A, Berrie E, Lawrie AM, Gilbert SC,Nicosia A, McConkey SJ, Hill AV.
PLoS One. 2014 Dec 18;9(12):e115161. doi: 10.1371/journal.pone.0115161. eCollection 2014.
162) Identification of a novel variant of epsilon-gamma-delta-beta° thalassemia highlights limitations of next generation sequencing.
Zebisch A, Schulz E, Grosso M, Lombardo B, Acierno G, Sill H, Iolascon A.
Am J Hematol. 2014 Dec 8. doi: 10.1002/ajh.23913. [Epub ahead of print] No abstract available.
161) Toxicity of Aflatoxin B1 towards the Vitamin D Receptor (VDR).
Costanzo P, Santini A, Fattore L, Novellino E, Ritieni A.
Food ChemToxicol. 2014 Dec 4. pii: S0278-6915(14)00498-0. doi: 10.1016/j.fct.2014.11.025. [Epub ahead of print]
160) HMGA1-pseudogene overexpression contributes to cancer progression.
Esposito F, De Martino M, Forzati F, Fusco A.
Cell Cycle. 2014 Oct 17:0. [Epub ahead of print]
159) Evaluation of salivary adiponectin profile in obese patients.
Nigro E, Piombino P, Scudiero O, Monaco ML, Schettino P, Chambery A, Daniele A.
Peptides. 2014 Dec 4. pii: S0196-9781(14)00342-8. doi: 10.1016/j.peptides.2014.11.007. [Epub ahead of print]
158) Cross-species toxicogenomic analyses and phenotypic anchoring in response to groundwater low-level pollution.
Porreca I, D Angelo F, Gentilcore D, Carchia E, Amoresano A, Affuso A, Ceccarelli M, De Luca P, Esposito L, Guadagno FM, Mallardo M, Nardone A, Maccarone S, Pane F, Scarfò M, Sordino P, De Felice M, Ambrosino C.
BMC Genomics. 2014 Dec 5;15(1):1067. [Epub ahead of print]
157) Evidence for Evolutionary and Nonevolutionary Forces Shaping the Distribution of Human Genetic Variants near Transcription Start Sites.
Scala G, Affinito O, Miele G, Monticelli A, Cocozza S.
PLoS One. 2014 Dec 4;9(12):e114432. doi: 10.1371/journal.pone.0114432. eCollection 2014.
156) Intracellular inactivation of thyroid hormone is a survival mechanism for muscle stem cell proliferation and lineage progression.
Dentice M, Ambrosio R, Damiano V, Sibilio A, Luongo C, Guardiola O, Yennek S, Zordan P, Minchiotti G, Colao A, Marsili A, Brunelli S, Del Vecchio L, Larsen PR, Tajbakhsh S, Salvatore D.
Cell Metab. 2014 Dec 2;20(6):1038-48. doi: 10.1016/j.cmet.2014.10.009. Epub 2014 Nov 13.
155) A defect in early myogenesis causes Otitis media in two mouse models of 22q11.2 deletion syndrome.
Fuchs JC, Linden JF, Baldini A, Tucker AS.
Hum Mol Genet. 2014 Dec 1. pii: ddu604. [Epub ahead of print]
154) A novel crosstalk between calcium/calmodulin kinases II and IV regulates cell proliferation in myeloid leukemia cells.
Monaco S, Rusciano MR, Maione AS, Soprano M, Gomathinayagam R, Todd LR, Campiglia P, Salzano S, Pastore L, Leggiero E, Wilkerson DC, Rocco M, Selleri C, Iaccarino G, Sankar U, Illario M.
Cell Signal. 2014 Nov 15. pii: S0898-6568(14)00353-2. doi: 10.1016/j.cellsig.2014.11.007. [Epub ahead of print]
153) Raf kinases in signal transduction and interaction with translation machinery.
Migliaccio N, Sanges C, Ruggiero I, Martucci NM, Rippa E, Arcari P, Lamberti A.
Biomol Concepts. 2013 Aug 1;4(4):391-9. doi: 10.1515/bmc-2013-0003.
152) Clinical and phenotypic features of CD5-negative B cell chronic lymphoproliferative disease resembling chronic lymphocytic leukemia.
Romano C, Sellitto A, Chiurazzi F, Simeone L, De Fanis U, Raia M, Del Vecchio L, Lucivero G.
Int J Hematol. 2014 Nov 29. [Epub ahead of print]
151) Comparison of binder compositions in Pompeian wall painting styles from Insula Occidentalis.
Gelzo M, Grimaldi M, Vergara A, Severino V, Chambery A, Dello Russo A, Piccioli C, Corso G,Arcari P.
Chem Cent J. 2014 Nov 20;8(1):65. eCollection 2014.
150) Chimpanzee Adenovirus Vector Ebola Vaccine – Preliminary Report.
Ledgerwood JE, DeZure AD, Stanley DA, Novik L, Enama ME, Berkowitz NM, Hu Z, Joshi G, Ploquin A, Sitar S, Gordon IJ, Plummer SA, Holman LA, Hendel CS, Yamshchikov G, Roman F, Nicosia A, Colloca S, Cortese R, Bailer RT, Schwartz RM, Roederer M, Mascola JR, Koup RA, Sullivan NJ, Graham BS; the VRC 207 Study Team.
N Engl J Med. 2014 Nov 26. [Epub ahead of print]
149) Genetics: The genomic landscape of papillary thyroid carcinoma.
Santoro M, Melillo RM.
Nat Rev Endocrinol. 2014 Nov 25. doi: 10.1038/nrendo.2014.209. [Epub ahead of print] No abstract available.
148) Refinement of Variant Selection for the LDL Cholesterol Genetic Risk Score in the Diagnosis of the Polygenic Form of Clinical Familial Hypercholesterolemia and Replication in Samples from 6 Countries.
Futema M, Shah S, Cooper JA, Li K, Whittall RA, Sharifi M, Goldberg O, Drogari E, Mollaki V, Wiegman A, Defesche J, D’Agostino MN, D’Angelo A, Rubba P, Fortunato G, Walus-Miarka M, Hegele RA, Aderayo Bamimore M, Durst R, Leitersdorf E, Mulder MT, Roeters van Lennep JE, Sijbrands EJ, Whittaker JC, Talmud PJ, Humphries SE.
Clin Chem. 2014 Nov 20. pii: clinchem.2014.231365. [Epub ahead of print]
147) High mobility group A1 protein expression reduces the sensitivity of colon and thyroid cancer cells to antineoplastic drugs.
D Angelo D, Mussnich P, Rosa R, Bianco R, Tortora G, Fusco A.
BMC Cancer. 2014 Nov 20;14(1):851. [Epub ahead of print]
146) Identification of Inquilinus limosus in Cystic Fibrosis: a first report in Italy.
Cicatiello AG, Iula DV, Pagliuca C, Pastore G, Pagliarulo C, Catania MR, Catania MR, Colicchio R, Picardi M, Raia V, Salvatore P.
New Microbiol. 2014 Jan;37(4):567-571. Epub 2014 Oct 1.
145) Transfer RNA and syndromic sideroblastic anemia.
Iolascon A.
Blood. 2014 Oct 30;124(18):2763-4. doi: 10.1182/blood-2014-09-600197. No abstract available.
144) A human vaccine strategy based on chimpanzee adenoviral and MVA vectors that primes, boosts, and sustains functional HCV-specific T cell memory.
Swadling L, Capone S, Antrobus RD, Brown A, Richardson R, Newell EW, Halliday J, Kelly C, Bowen D, Fergusson J, Kurioka A, Ammendola V, Del Sorbo M, Grazioli F, Esposito ML, Siani L, Traboni C, Hill A, Colloca S, Davis M, Nicosia A, Cortese R, Folgori A, Klenerman P, Barnes E.
Sci Transl Med. 2014 Nov 5;6(261):261ra153. doi: 10.1126/scitranslmed.3009185.
143) Structural Model of the hUbA1-UbcH10 Quaternary Complex: In Silico and Experimental Analysis of the Protein-Protein Interactions between E1, E2 and Ubiquitin.
Correale S, de Paola I, Morgillo CM, Federico A, Zaccaro L, Pallante P, Galeone A, Fusco A, Pedone E, Luque FJ, Catalanotti B.
PLoS One. 2014 Nov 6;9(11):e112082. doi: 10.1371/journal.pone.0112082. eCollection 2014.
142) Serum metabolomic profiles suggest influence of sex and oral contraceptive use.
Ruoppolo M, Campesi I, Scolamiero E, Pecce R, Caterino M, Cherchi S, Mercuro G, Tonolo G, Franconi F.
Am J Transl Res. 2014 Oct 11;6(5):614-24. eCollection 2014.
141) Cell-Surface Receptors Transactivation Mediated by G Protein-Coupled Receptors.
Cattaneo F, Guerra G, Parisi M, De Marinis M, Tafuri D, Cinelli M, Ammendola R.
Int J Mol Sci. 2014 Oct 29;15(11):19700-19728. Review.
140) MiR-34a deficiency accelerates medulloblastoma formation in vivo.
Thor T, Künkele A, Pajtler KW, Wefers AK, Stephan H, Mestdagh P, Heukamp L, Hartmann W, Vandesompele J, Sadowski N, Becker L, Garrett L, Hölter SM, Horsch M, Calzada-Wack J, Klein-Rodewald T, Racz I, Zimmer A, Beckers J, Neff F, Klopstock T, De Antonellis P, Zollo M, Wurst W, Fuchs H, Gailus-Durner V, Schüller U, Hraběde Angelis M, Eggert A, Schramm A, Schulte JH.
Int J Cancer. 2014 Oct 27. doi: 10.1002/ijc.29294. [Epub ahead of print]
139) Dramatic Potentiation of the Antiviral Activity of HIV Antibodies by Cholesterol Conjugation.
Lacek K, Urbanowicz RA, Troise F, De Lorenzo C, Severino V, Di Maro A, Tarr AW, Ferrara F, Ploss A, Temperton N, Ball JK, Nicosia A, Cortese R, Pessi A.
J Biol Chem. 2014 Oct 23. pii: jbc.M114.591826. [Epub ahead of print]
138) Proteolytic control of neurite outgrowth inhibitor NOGO-A by the cAMP/PKA pathway.
Sepe M, Lignitto L, Porpora M, Delle Donne R, Rinaldi L, Belgianni G, Colucci G, Cuomo O, Viggiano D, Scorziello A, Garbi C, Annunziato L, Feliciello A.
Proc Natl Acad Sci U S A. 2014 Oct 20. pii: 201410274. [Epub ahead of print]
137) Evaluation of the Efficacy of ChAd63-MVA Vectored Vaccines Expressing CS & ME-TRAP Against Controlled Human Malaria Infection in Malaria Naïve Individuals.
Hodgson SH, Ewer KJ, Bliss CM, Edwards NJ, Rampling T, Anagnostou NA, de Barra E, Havelock T, Bowyer G, Poulton ID, de Cassan S, Illingworth JJ, Douglas AD, Mange PB, Collins KA, Roberts R, Gerry S, Berrie E, Moyle S, Colloca S, Cortese R, Sinden RE, Gilbert SC, Bejon P, Lawrie AM, Nicosia A, Faust SN, Hill AV.
J Infect Dis. 2014 Oct 21. pii: jiu579. [Epub ahead of print]
136) Mechanism of retinoic acid-induced transcription: histone code, DNA oxidation and formation of chromatin loops.
Zuchegna C, Aceto F, Bertoni A, Romano A, Perillo B, Laccetti P, Gottesman ME, Avvedimento EV, Porcellini A.
Nucleic Acids Res. 2014 Oct 15. pii: gku958. [Epub ahead of print] No abstract available.
135) Common genetic variants in NEFL influence gene expression and neuroblastoma risk.
Capasso M, Diskin SJ, Cimmino F, Acierno G, Totaro F, Petrosino G, Pezone L, Diamond M, McDaniel L, Hakonarson H, Iolascon A, Devoto M, Maris JM.
Cancer Res. 2014 Oct 13. pii: canres.0431.2014. [Epub ahead of print]
135) Cancer-Selective Targeting of the NF-κB Survival Pathway with GADD45β/MKK7 Inhibitors.
Tornatore L, Sandomenico A, Raimondo D, Low C, Rocci A, Tralau-Stewart C, Capece D, D’Andrea D, Bua M, Boyle E, van Duin M, Zoppoli P, Jaxa-Chamiec A, Thotakura AK, Dyson J, Walker BA,Leonardi A, Chambery A, Driessen C, Sonneveld P, Morgan G, Palumbo A, Tramontano A, Rahemtulla A, Ruvo M, Franzoso G.
Cancer Cell. 2014 Oct 13;26(4):495-508. doi: 10.1016/j.ccr.2014.07.027.
134) Analysis of extracellular superoxide dismutase and Akt in ascending aortic aneurysm with tricuspid or bicuspid aortic valve.
Arcucci A, Ruocco MR, Albano F, Granato G, Romano V, Corso G, Bancone C, De Vendittis E, Della Corte A, Montagnani S.
Eur J Histochem. 2014 Jul 18;58(3):2383. doi: 10.4081/ejh.2014.2383.
133) Association of USF1 and APOA5 polymorphisms with Familial Combined Hyperlipidemia in an Italian population.
Di Taranto MD, Staiano A, D’Agostino MN, D’Angelo A, Bloise E, Morgante A, Marotta G, Gentile M, Rubba P, Fortunato G.
Mol Cell Probes. 2014 Oct 9. pii: S0890-8508(14)00048-6. doi: 10.1016/j.mcp.2014.10.002. [Epub ahead of print]
132) New therapeutic perspectives in CCDC6 deficient lung cancer cells.
Morra F, Luise C, Visconti R, Staibano S, Merolla F, Ilardi G, Guggino G, Paladino S, Sarnataro D, Franco R, Monaco R, Zitomarino F, Pacelli R, Monaco G, Rocco G, Cerrato A, Linardopoulos S, Muller MT, Celetti A.
Int J Cancer. 2014 Oct 10. doi: 10.1002/ijc.29263. [Epub ahead of print]
131) The adipokine apelin-13 induces expression of prothrombotic tissue factor.
Cirillo P, Ziviello F, Pellegrino G, Conte S, Cimmino G, Giaquinto A, Pacifico F, Leonardi A, Golino P, Trimarco B.
Thromb Haemost. 2014 Oct 9;113(1). [Epub ahead of print]
130) A novel polymorphism in the PAI-1 gene promoter enhances gene expression. A novel pro-thrombotic risk factor?
Liguori R, Quaranta S, Di Fiore R, Elce A, Castaldo G, Amato F.
Thromb Res. 2014 Sep 28. pii: S0049-3848(14)00506-4. doi: 10.1016/j.thromres.2014.09.021. [Epub ahead of print]
129) HMGA1 pseudogenes as candidate proto-oncogenic competitive endogenous RNAs.
Esposito F, De Martino M, Petti MG, Forzati F, Tornincasa M, Federico A, Arra C, Pierantoni GM, Fusco A.
Oncotarget. 2014 Jul 15. [Epub ahead of print]
128) The formyl peptide receptor 1 exerts a tumor suppressor function in human gastric cancer by inhibiting angiogenesis.
Prevete N, Liotti F, Visciano C, Marone G, Melillo RM, de Paulis A.
Oncogene. 2014 Sep 29. doi: 10.1038/onc.2014.309. [Epub ahead of print]
127) Hypomorphic NOTCH3 mutation in an Italian family with CADASIL features.
Moccia M, Mosca L, Erro R, Cervasio M, Allocca R, Vitale C, Leonardi A, Caranci F, Del Basso-De Caro ML, Barone P, Penco S.
Neurobiol Aging. 2014 Aug 27. pii: S0197-4580(14)00534-X. doi: 10.1016/j.neurobiolaging.2014.08.021. [Epub ahead of print]
126) DNA methylation state of BDNF gene is not altered in prefrontal cortex and striatum of schizophrenia subjects.
Keller S, Errico F, Zarrilli F, Florio E, Punzo D, Mansueto S, Angrisano T, Pero R, Lembo F, Castaldo G, Usiello A, Chiariotti L.
Psychiatry Res. 2014 Aug 28. pii: S0165-1781(14)00718-5. doi: 10.1016/j.psychres.2014.08.022. [Epub ahead of print]
125) Congenital Erythropoietic Porphyria linked to GATA1-R216W mutation: challenges for diagnosis.
Di Pierro E, Russo R, Karakas Z, Brancaleoni V, Gambale A, Kurt I, Winter SS, Granata F, Czuchlewski DR, Langella C, Iolascon A, Cappellini MD.
Eur J Haematol. 2014 Sep 23. doi: 10.1111/ejh.12452. [Epub ahead of print]
124) Statins and contrast-induced acute kidney injury.
Briguori C, Napolitano G, Condorelli G.
Coron Artery Dis. 2014 Nov;25(7):550-1. doi: 10.1097/MCA.0000000000000154. No abstract available.
123) RET Recognition of GDNF-GFRα1 Ligand by a Composite Binding Site Promotes Membrane-Proximal Self-Association.
Goodman KM, Kjær S, Beuron F, Knowles PP, Nawrotek A, Burns EM, Purkiss AG, George R,Santoro M, Morris EP, McDonald NQ.
Cell Rep. 2014 Sep 17. pii: S2211-1247(14)00716-5. doi: 10.1016/j.celrep.2014.08.040. [Epub ahead of print]
122) TRAP1 is involved in BRAF regulation and downstream attenuation of ERK phosphorylation and cell cycle progression: a novel target for BRAF-mutated colorectal tumors.
Condelli V, Piscazzi A, Sisinni L, Matassa DS, Maddalena F, Lettini G, Simeon V, Palladino G, Amoroso MR, Trino S, Esposito F, Landriscina M.
Cancer Res. 2014 Sep 19. pii: canres.1331.2014. [Epub ahead of print]
121) miR-142-3p downregulation contributes to thyroid follicular tumorigenesis by targeting ASH1L and MLL1.
Colamaio M, Puca F, Ragozzino E, Gemei M, Decaussin-Petrucci M, Aiello C, Bastos AU, Federico A, Chiappetta G, Vecchio LD, Torregrossa L, Battista S, Fusco A.
J ClinEndocrinolMetab. 2014 Sep 19:jc20142280. [Epub ahead of print]
120) Diatomite biosilica nanocarriers for siRNA transport inside cancer cells.
Rea I, Martucci NM, De Stefano L, Ruggiero I, Terracciano M, Dardano P, Migliaccio N, Arcari P, Taté R, Rendina I, Lamberti A.
Biochim Biophys Acta. 2014 Sep 12. pii: S0304-4165(14)00311-0. doi: 10.1016/j.bbagen.2014.09.009. [Epub ahead of print]
119) Mechanism of retinoic acid-induced transcription: histone code, DNA oxidation and formation of chromatin loops.
Zuchegna C, Aceto F, Bertoni A, Romano A, Perillo B, Laccetti P, Gottesman ME, Avvedimento EV, Porcellini A.
Nucleic Acids Res. 2014 Sep 12. pii: gku823. [Epub ahead of print]
118) Identification of two novel RET kinase inhibitors through MCR-based drug discovery: Design, synthesis and evaluation.
Frett B, Moccia M, Carlomagno F, Santoro M, Li HY.
Eur J Med Chem. 2014 Sep 8;86C:714-723. doi: 10.1016/j.ejmech.2014.09.023. [Epub ahead of print]
117) Sterol and steroid catabolites from cholesterol produced by the psychrophile Pseudoalteromonas haloplanktis.
Gelzo M, Lamberti A, Spano G, Dello Russo A, Corso G, Masullo M.
J Mass Spectrom. 2014 Sep;49(9):947-51. doi: 10.1002/jms.3459.
116) MTHFR C677T allelic variant is not associated to plasma and cerebrospinal fluid homocysteine in amyotrophic lateral sclerosis.
Bellia C, Bivona G, Caruso A, Elce A, Amato F, Spataro R, Colletti T, Pivetti A, Russo V, Scazzone C, Lo Sasso B, Castaldo G, La Bella V, Ciaccio M.
Clin Chem Lab Med. 2014 Sep 17. pii: /j/cclm.ahead-of-print/cclm-2014-0465/cclm-2014-0465.xml. doi: 10.1515/cclm-2014-0465. [Epub ahead of print] No abstract available.
115) ABCG2, a novel antigen to sort luminal progenitors of BRCA1- breast cancer cells.
Leccia F, Del Vecchio L, Mariotti E, Di Noto R, Morel AP, Puisieux A, Salvatore F, Ansieau S.
Mol Cancer. 2014 Sep 12;13(1):213. [Epub ahead of print]
114) p53 suppression partially rescues the mutant phenotype in mouse models of DiGeorge syndrome.
Caprio C, Baldini A.
Proc Natl Acad Sci U S A. 2014 Sep 2. pii: 201401923. [Epub ahead of print]
113) Chimpanzee adenovirus vaccine generates acute and durable protective immunity against ebolavirus challenge.
Stanley DA, Honko AN, Asiedu C, Trefry JC, Lau-Kilby AW, Johnson JC, Hensley L, Ammendola V, Abbate A, Grazioli F, Foulds KE, Cheng C, Wang L, Donaldson MM, Colloca S, Folgori A, Roederer M, Nabel GJ, Mascola J, Nicosia A, Cortese R, Koup RA, Sullivan NJ.
Nat Med. 2014 Sep 7. doi: 10.1038/nm.3702. [Epub ahead of print]
112) Screening in Planarians Identifies MORN2 as a Key Component in LC3-Associated Phagocytosis and Resistance to Bacterial Infection.
Abnave P, Mottola G, Gimenez G, Boucherit N, Trouplin V, Torre C, Conti F, Ben Amara A, Lepolard C, Djian B, Hamaoui D, Mettouchi A, Kumar A, Pagnotta S, Bonatti S, Lepidi H, Salvetti A, Abi-Rached L, Lemichez E, Mege JL, Ghigo E.
Cell Host Microbe. 2014 Sep 10;16(3):338-350. doi: 10.1016/j.chom.2014.08.002.
111) Maternal Vitamin B12 deficiency detected in expanded newborn screening.
Scolamiero E, Villani GR, Ingenito L, Pecce R, Albano L, Caterino M, di Girolamo MG, Di Stefano C, Franzese I, Gallo G, Ruoppolo M.
Clin Biochem. 2014 Sep 6. pii: S0009-9120(14)00655-9. doi: 10.1016/j.clinbiochem.2014.08.020. [Epub ahead of print]
110) Mass spectrometric/bioinformatic identification of a protein subset that characterizes the cellular activity of anticancer peptides.
Genovese F, Gualandi A, Taddia L, Marverti G, Pirondi S, Marraccini C, Perco P, Pela M, Guerrini R, Amoroso MR, Esposito F, Martello A, Ponterini G, D’Arca D, Costi MP.
J Proteome Res. 2014 Sep 8. [Epub ahead of print]
109) Test meals rich in marine long-chain n-3 polyunsaturated fatty acids increase postprandial chylomicron response.
Griffo E, Di Marino L, Patti L, Bozzetto L, Annuzzi G, Cipriano P, Mangione A, Della Pepa G, Cocozza S, Riccardi G, Rivellese AA.
Nutr Res. 2014 Aug;34(8):661-6. doi: 10.1016/j.nutres.2014.07.005. Epub 2014 Jul 10.
108) CBX7 gene expression plays a negative role in adipocyte cell growth and differentiation.
Forzati F, Federico A, Pallante P, Colamaio M, Esposito F, Sepe R, Gargiulo S, Luciano A, Arra C, Palma G, Bon G, Bucher S, Falcioni R, Brunetti A, Battista S, Fedele M, Fusco A.
Biol Open. 2014 Sep 4. pii: BIO20147872. doi: 10.1242/bio.20147872. [Epub ahead of print]
107) Oxidative DNA damage induces the ATM-mediated transcriptional suppression of the Wnt inhibitor WIF-1 in systemic sclerosis and fibrosis.
Svegliati S, Marrone G, Pezone A, Spadoni T, Grieco A, Moroncini G, Grieco D, Vinciguerra M, Agnese S, Jüngel A, Distler O, Musti AM, Gabrielli A, Avvedimento EV.
Sci Signal. 2014 Sep 2;7(341):ra84. doi: 10.1126/scisignal.2004592.
106) Effect of p53 activity on the sensitivity of human glioblastoma cells to PARP-1 inhibitor in combination with topoisomerase i inhibitor or radiation.
Sabbatino F, Fusciello C, Somma D, Pacelli R, Poudel R, Pepin D, Leonardi A, Carlomagno C, Della Vittoria Scarpati G, Ferrone S, Pepe S.
Cytometry A. 2014 Sep 2. doi: 10.1002/cyto.a.22563. [Epub ahead of print]
105) Epigenetic switch at atp2a2 and myh7 gene promoters in pressure overload-induced heart failure.
Angrisano T, Schiattarella GG, Keller S, Pironti G, Florio E, Magliulo F, Bottino R, Pero R, Lembo F,Avvedimento EV, Esposito G, Trimarco B, Chiariotti L, Perrino C.
PLoS One. 2014 Sep 2;9(9):e106024. doi: 10.1371/journal.pone.0106024. eCollection 2014.
104) Analysis of the interactome of ribosomal protein 19 mutants.
Caterino M, Aspesi A, Pavesi E, Imperlini E, Pagnozzi D, Ingenito L, Santoro C, Dianzani I, Ruoppolo M.
Proteomics. 2014 Jul 28. doi: 10.1002/pmic.201300513. [Epub ahead of print]
103) Novel INF2 mutations in an Italian cohort of patients with focal segmental glomerulosclerosis, renal failure and Charcot-Marie-Tooth neuropathy.
Caridi G, Lugani F, Dagnino M, Gigante M, Iolascon A, Falco M, Graziano C, Benetti E, Dugo M, Del Prete D, Granata A, Borracelli D, Moggia E, Quaglia M, Rinaldi R, Gesualdo L, Ghiggeri GM.
Nephrol Dial Transplant. 2014 Sep;29 Suppl 4:iv80-iv86. doi: 10.1093/ndt/gfu071.
102) Functional and Clinical Impact of Novel TMPRSS6 Variants in Iron-Refractory Iron-Deficiency Anaemia Patients and Genotype-Phenotype Studies.
Falco LD, Silvestri L, Kannengiesser C, Morán E, Oudin C, Rausa M, Bruno M, Aranda J, Argiles B, Yenicesu I, Falcon-Rodriguez M, Yilmaz-Keskin E, Kocak U, Beaumont C, Camaschella C, Iolascon A, Grandchamp B, Sanchez M.
Hum Mutat. 2014 Aug 25. doi: 10.1002/humu.22632. [Epub ahead of print]
101) Combining viral vectored and protein-in-adjuvant vaccines against the blood-stage malaria antigen AMA1 – Report on a Phase Ia clinical trial.
Hodgson SH, Choudhary P, Elias SC, Milne KH, Rampling TW, Biswas S, Poulton ID, Miura K, Douglas AD, Alanine DG, Illingworth JJ, de Cassan SC, Nicosia A, Long CA, Moyle S, Berrie E, Lawrie AM, Wu Y, Ellis RD, Hill AV, Draper SJ.
Mol Ther. 2014 Aug 26. doi: 10.1038/mt.2014.157. [Epub ahead of print]
100) miR-340 inhibits tumor cell proliferation and induces apoptosis by targeting multiple negative regulators of p27 in non-small cell lung cancer.
Fernandez S, Risolino M, Mandia N, Talotta F, Soini Y, Incoronato M, Condorelli G, Banfi S, Verde P.
Oncogene. 2014 Aug 25;0. doi: 10.1038/onc.2014.267. [Epub ahead of print]
99) Anti-amyloidogenic property of human gastrokine 1.
Altieri F, Di Stadio CS, Severino V, Sandomenico A, Minopoli G, Miselli G, Di Maro A, Ruvo M, Chambery A, Quagliariello V, Masullo M, Rippa E, Arcari P.
Biochimie. 2014 Aug 16. pii: S0300-9084(14)00222-3. doi: 10.1016/j.biochi.2014.08.004. [Epub ahead of print]
98) Role of the hypervariable region 1 (HVR1) for the interplay of hepatitis C virus with entry factors and lipoproteins.
Bankwitz D, Vieyres G, Hueging K, Bitzegeio J, Doepke M, Chhatwal P, Haid S, Catanese MT, Zeisel MB,Nicosia A, Baumert TF, Kaderali L, Pietschmann T.
J Virol. 2014 Aug 20. pii: JVI.01145-14. [Epub ahead of print]
97) A therapeutic approach to treat prostate cancer by targeting Nm23-H1/h-Prune interaction.
Carotenuto M, de Antonellis P, Chiarolla CM, Attanasio C, Damiani V, Boffa I, Aiese N, Pedone E, Accordi B, Basso G, Navas L, Imbimbo C, Zollo M.
Naunyn Schmiedebergs Arch Pharmacol. 2014 Aug 20. [Epub ahead of print]
96) Dysfunctional dopaminergic neurotransmission in asocial BTBR mice.
Squillace M, Dodero L, Federici M, Migliarini S, Errico F, Napolitano F, Krashia P, Di Maio A, Galbusera A, Bifone A, Scattoni ML, Pasqualetti M, Mercuri NB, Usiello A, Gozzi A.
Transl Psychiatry. 2014 Aug 19;4:e427. doi: 10.1038/tp.2014.69.
95) Genetic diseases that predispose to early liver cirrhosis.
Scorza M, Elce A, Zarrilli F, Liguori R, Amato F, Castaldo G.
Int J Hepatol. 2014;2014:713754. doi: 10.1155/2014/713754. Epub 2014 Jul 14. Review.
94) EARLY SURGERY AND SURVIVAL OF PATIENTS WITH ANAPLASTIC THYROID CARCINOMA: ANALYSIS OF A CASE SERIES REFERRED TO A SINGLE INSTITUTION BETWEEN 1999 – 2012.
Brignardello E, Palestini N, Felicetti F, Castiglione A, Piovesan A, Gallo M, Freddi M, Ricardi U, Gasparri G, Ciccone G, Arvat E, Boccuzzi G.
Thyroid. 2014 Aug 11. [Epub ahead of print]
93) New Insight into Adiponectin Role in Obesity and Obesity-Related Diseases.
Nigro E, Scudiero O, Monaco ML, Palmieri A, Mazzarella G, Costagliola C, Bianco A, Daniele A.
Biomed Res Int. 2014;2014:658913. Epub 2014 Jul 7. Review.
92) Tropomyosin-related kinase B receptor polymorphisms and isoforms expression in suicide victims.
Zarrilli F, Amato F, Keller S, Florio E, Carli V, Stuppia L, Sarchiapone M, Chiariotti L, Castaldo G,Tomaiuolo R.
Psychiatry Res. 2014 Jul 28. pii: S0165-1781(14)00615-5. doi: 10.1016/j.psychres.2014.07.036. [Epub ahead of print] No abstract available.
91) ER Reorganization is Remarkably Induced in COS-7 Cells Accumulating Transmembrane Protein Receptors Not Competent for Export from the Endoplasmic Reticulum.
D’Agostino M, Crespi A, Polishchuk E, Generoso S, Martire G, Colombo SF, Bonatti S.
J Membr Biol. 2014 Aug 3. [Epub ahead of print]
90) Inhibition of Hedgehog signalling by NVP-LDE225 (Erismodegib) interferes with growth and invasion of human renal cell carcinoma cells.
D’Amato C, Rosa R, Marciano R, D’Amato V, Formisano L, Nappi L, Raimondo L, Di Mauro C, Servetto A, Fulciniti F, Cipolletta A, Bianco C, Ciardiello F, Veneziani BM, De Placido S, Bianco R.
Br J Cancer. 2014 Aug 5. doi: 10.1038/bjc.2014.421. [Epub ahead of print]
89) Protease Nexin-1 affects the migration and invasion of C6 glioma cells through the regulation of urokinase Plasminogen Activator and Matrix Metalloproteinase-9/2.
Pagliara V, Adornetto A, Mammì M, Masullo M, Sarnataro D, Pietropaolo C, Arcone R.
Biochim Biophys Acta. 2014 Jul 27. pii: S0167-4889(14)00285-7. doi: 10.1016/j.bbamcr.2014.07.008. [Epub ahead of print]
88) Free D-aspartate regulates neuronal dendritic morphology, synaptic plasticity, gray matter volume and brain activity in mammals.
Errico F, Nisticò R, Di Giorgio A, Squillace M, Vitucci D, Galbusera A, Piccinin S, Mango D, Fazio L, Middei S, Trizio S, Mercuri NB, Teule MA, Centonze D, Gozzi A, Blasi G, Bertolino A, Usiello A.
Transl Psychiatry. 2014 Jul 29;4:e417. doi: 10.1038/tp.2014.59.
87) Retrospective cohort study of 205 cases with congenital dyserythropoietic anemia type II: Definition of clinical and molecular spectrum and identification of new diagnostic scores.
Russo R, Gambale A, Langella C, Andolfo I, Unal S, Iolascon A.
Am J Hematol. 2014 Jul 9. doi: 10.1002/ajh.23800. [Epub ahead of print]
86) Mucopolysaccharidosis type II in a female patient with a reciprocal X;9 translocation and skewed X chromosome inactivation.
Lonardo F, Di Natale P, Lualdi S, Acquaviva F, Cuoco C, Scarano F, Maioli M, Pavone LM, Di Gregorio G, Filocamo M, Scarano G.
Am J Med Genet A. 2014 Jul 8. doi: 10.1002/ajmg.a.36667. [Epub ahead of print]
85) Hereditary xerocytosis revisited.
Archer NM, Shmukler BE, Andolfo I, Vandorpe DH, Gnanasambandam R, Higgins JM, Rivera A, Fleming MD, Sachs F, Gottlieb PA, Iolascon A, Brugnara C, Alper SL, Nathan DG.
Am J Hematol. 2014 Jul 5. doi: 10.1002/ajh.23799. [Epub ahead of print] No abstract available.
84) Significance of Sarcomere Gene Mutations Analysis in the End-Stage Phase of Hypertrophic Cardiomyopathy.
Biagini E, Olivotto I, Iascone M, Parodi MI, Girolami F, Frisso G, Autore C, Limongelli G, Cecconi M, Maron BJ, Maron MS, Rosmini S, Formisano F, Musumeci B, Cecchi F, Iacovoni A, Haas TS, Bacchi Reggiani ML, Ferrazzi P, Salvatore F, Spirito P, Rapezzi C.
Am J Cardiol. 2014 Jun 19. pii: S0002-9149(14)01309-5. doi: 10.1016/j.amjcard.2014.05.065. [Epub ahead of print]
83) H-Prune through GSK-3β interaction sustains canonical WNT/β-catenin signaling enhancing cancer progression in NSCLC.
Carotenuto M, De Antonellis P, Liguori L, Benvenuto G, Magliulo D, Alonzi A, Turino C, Attanasio C, Damiani V, Bello AM, Vitiello F, Pasquinelli R, Terracciano L, Federico A, Fusco A, Freeman J, Dale TC, Decraene C, Chiappetta G, Piantedosi F, Calabrese C, Zollo M.
Oncotarget. 2014 Jul 5. [Epub ahead of print]
82) Diatomite silica nanoparticles for drug delivery.
Ruggiero I, Terracciano M, Martucci NM, De Stefano L, Migliaccio N, Tatè R, Rendina I, Arcari P,Lamberti A, Rea I.
Nanoscale Res Lett. 2014 Jul 3;9(1):329. doi: 10.1186/1556-276X-9-329. eCollection 2014.
81) Pearls & Oy-sters: Familial epileptic encephalopathy due to methylenetetrahydrofolate reductase deficiency.
Cappuccio G, Cozzolino C, Frisso G, Romanelli R, Parenti G, D’Amico A, Carotenuto B, Salvatore F, Del Giudice E.
Neurology. 2014 Jul 15;83(3):e41-4. doi: 10.1212/WNL.0000000000000591. No abstract available.
80) Serotonin activates cell survival and apoptotic death responses in cultured epithelial thyroid cells.
Cerulo G, Tafuri S, De Pasquale V, Rea S, Romano S, Costagliola A, Della Morte R, Avallone L,Pavone LM.
Biochimie. 2014 Jul 2. pii: S0300-9084(14)00173-4. doi: 10.1016/j.biochi.2014.06.020. [Epub ahead of print]
79)ABT-450: A Novel Protease Inhibitor For the Treatment of Hepatitis C Virus Infection.
Gentile I, Borgia F, Buonomo AR, Zappulo E, Castaldo G, Borgia G.
Curr Med Chem. 2014 Jul 6. [Epub ahead of print]
78) TRAP1 revisited: Novel localizations and functions of a ‘next-generation’ biomarker (Review).
Amoroso MR, Matassa DS, Sisinni L, Lettini G, Landriscina M, Esposito F.
Int J Oncol. 2014 Sep;45(3):969-77. doi: 10.3892/ijo.2014.2530. Epub 2014 Jun 27.
77) Prolonged Activated Partial Thromboplastin Time: Difficulties in Discriminating Coexistent Factor VIII Inhibitor and Lupus Anticoagulant.
Ames PR, Graf M, Archer J, Scarpato N, Iannaccone L.
Clin Appl Thromb Hemost. 2014 Jul 2. pii: 1076029614541516. [Epub ahead of print]
76) Anterior gradient protein 2 promotes survival, migration and invasion of papillary thyroid carcinoma cells.
Di Maro G, Salerno P, Unger K, Orlandella FM, Monaco M, Chiappetta G, Thomas G, Oczko-Wojciechowska M, Masullo M, Jarzab B, Santoro M, Salvatore G.
Mol Cancer. 2014 Jun 30;13(1):160. [Epub ahead of print]
75) Novel Biomarkers for Contrast-Induced Acute Kidney Injury.
Briguori C, Quintavalle C, Donnarumma E, Condorelli G.
Biomed Res Int. 2014;2014:568738. Epub 2014 May 29. Review.
74) T cell immunity and HCV reinfection after cure of chronic hepatitis C with an interferon-free antiviral regimen.
Callendret B, Eccleston HB, Hall S, Satterfield W, Capone S, Folgori A, Cortese R, Nicosia A, Walker CM.
Hepatology. 2014 Jun 26. doi: 10.1002/hep.27278. [Epub ahead of print]
73) TRAP1-dependent regulation of p70S6K is involved in the attenuation of protein synthesis and cell migration: Relevance in human colorectal tumors.
Matassa DS, Agliarulo I, Amoroso MR, Maddalena F, Sepe L, Ferrari MC, Sagar V, D’Amico S, Loreni F, Paolella G, Landriscina M, Esposito F.
Mol Oncol. 2014 Jun 13. pii: S1574-7891(14)00127-6. doi: 10.1016/j.molonc.2014.06.003. [Epub ahead of print]
72) NCOA4 Transcriptional Coactivator Inhibits Activation of DNA Replication Origins.
Bellelli R, Castellone MD, Guida T, Limongello R, Dathan NA, Merolla F, Cirafici AM, Affuso A, Masai H, Costanzo V, Grieco D, Fusco A, Santoro M, Carlomagno F.
Mol Cell. 2014 Jun 4. pii: S1097-2765(14)00365-7. doi: 10.1016/j.molcel.2014.04.031. [Epub ahead of print]
71) Enhanced Vaccine-Induced CD8+ T Cell Responses to Malaria Antigen ME-TRAP by Fusion to MHC Class II Invariant Chain.
Spencer AJ, Cottingham MG, Jenks JA, Longley RJ, Capone S, Colloca S, Folgori A, Cortese R,Nicosia A, Bregu M, Hill AV.
PLoS One. 2014 Jun 19;9(6):e100538. doi: 10.1371/journal.pone.0100538. eCollection 2014.
70) Wilson Disease Protein ATP7B Utilizes Lysosomal Exocytosis to Maintain Copper Homeostasis.
Polishchuk EV, Concilli M, Iacobacci S, Chesi G, Pastore N, Piccolo P, Paladino S, Baldantoni D, van IJzendoorn SC, Chan J, Chang CJ, Amoresano A, Pane F, Pucci P, Tarallo A, Parenti G, Brunetti-Pierri N, Settembre C, Ballabio A, Polishchuk RS.
Dev Cell. 2014 Jun 4. pii: S1534-5807(14)00280-9. doi: 10.1016/j.devcel.2014.04.033. [Epub ahead of print]
69) Sorting of GPI-anchored proteins from yeast to mammals – common pathways at different sites?
Muñiz M, Zurzolo C.
J Cell Sci. 2014 Jun 6. pii: jcs.148056. [Epub ahead of print]
68) Growth factor transduction pathways: paradigm of anti-neoplastic targeted therapy.
Carlomagno F, Chiariello M.
J Mol Med (Berl). 2014 Jun 8. [Epub ahead of print]
67) Comparative Analysis of Gene Expression Data Reveals Novel Targets of Senescence-Associated microRNAs.
Napolitano M, Comegna M, Succoio M, Leggiero E, Pastore L, Faraonio R, Cimino F, Passaro F.
PLoS One. 2014 Jun 6;9(6):e98669. doi: 10.1371/journal.pone.0098669. eCollection 2014.
66) Production and characterization of high-titer serum-free cell culture grown hepatitis C virus particles of genotype 1-6.
Mathiesen CK, Jensen TB, Prentoe J, Krarup H, Nicosia A, Law M, Bukh J, Gottwein JM.
Virology. 2014 Jun;458-459:190-208. doi: 10.1016/j.virol.2014.03.021. Epub 2014 May 24.
65) Laparoscopic Adjustable Gastric Banding Reduces Subcutaneous Adipose Tissue and Blood Inflammation in Nondiabetic Morbidly Obese Individuals.
Iaffaldano L, Nardelli C, Pilone V, Labruna G, Alfieri A, Montanaro D, Ferrigno M, Zeccolella MR, Carlomagno N, Renda A, Baldi A, Forestieri P, Sacchetti L, Buono P.
Obes Surg. 2014 Jun 13. [Epub ahead of print]
64) Early targets of miR-34a in neuroblastoma.
de Antonellis P, Carotenuto M, Vandenbussche J, De Vita G, Ferrucci V, Medaglia C, Boffa I, Galiero A, Di Somma S, Magliulo D, Aiese N, Alonzi A, Spano D, Liguori L, Chiarolla C, Verrico A, Schulte JH, Mestdagh P, Vandesompele J, Gevaert K, Zollo M.
Mol Cell Proteomics. 2014 Jun 9. pii: mcp.M113.035808. [Epub ahead of print]
63) Hormonogenic donor Tyr2522 of bovine thyroglobulin. Insight into preferential T3 formation at thyroglobulin carboxyl terminus at low iodination level.
Cetrangolo GP, Arcaro A, Lepore A, Graf M, Mamone G, Ferranti P, Palumbo G, Gentile F.
Biochem Biophys Res Commun. 2014 Jun 6. pii: S0006-291X(14)01050-X. doi: 10.1016/j.bbrc.2014.05.144. [Epub ahead of print]
62) Epidermal growth factor receptor activation modulates Src-dependent resistance to lapatinib in breast cancer models.
Formisano L, Nappi L, Rosa R, Marciano R, D Amato C, D Amato V, Damiano V, Raimondo L, Iommelli F, Scorziello A, Troncone G, Veneziani BM, Parsons SJ, De Placido S, Bianco R.
Breast Cancer Res. 2014 May 5;16(3):R45. [Epub ahead of print]
61) Defined alpha-synuclein prion-like molecular assemblies spreading in cell culture.
Auli S, Le TT, Moda F, Abounit S, Corvaglia S, Casalis L, Gustincich S, Zurzolo C, Tagliavini F, Legname G.
BMC Neurosci. 2014 Jun 4;15(1):69. [Epub ahead of print]
60) Serotonin regulates contractile activity of the uterus in non-pregnant rabbits.
Lychkova AE, De Pasquale V, Avallone L, Puzikov AM, Pavone LM.
Comp BiochemPhysiol C ToxicolPharmacol. 2014 May 31. pii: S1532-0456(14)00079-9. doi: 10.1016/j.cbpc.2014.05.006. [Epub ahead of print]
59) Complete sequencing of Novosphingobium sp. PP1Y reveals a biotechnologicallymeaningfulmetabolic pattern.
D Argenio V, Notomista E, Petrillo M, Cantiello P, Cafaro V, Izzo V, Naso B, Cozzuto L, Durante L, Troncone L, Paolella G, Salvatore F, Di Donato A.
BMC Genomics. 2014 May 19;15(1):384. [Epub ahead of print]
58) Identification of miR-494 direct targets involved in senescence of human diploid fibroblasts.
Comegna M, Succoio M, Napolitano M, Vitale M, D’Ambrosio C, Scaloni A, Passaro F, Zambrano N, Cimino F, Faraonio R.
FASEB J. 2014 May 13. pii: fj.13-239129. [Epub ahead of print]
57) CBX7 Modulates the Expression of Genes Critical for Cancer Progression.
Pallante P, Sepe R, Federico A, Forzati F, Bianco M, Fusco A.
PLoS One. 2014 May 27;9(5):e98295. doi: 10.1371/journal.pone.0098295. eCollection 2014.
56) Is it time to revise the normal range of serum uric acid levels?
Desideri G, Castaldo G, Lombardi A, Mussap M, Testa A, Pontremoli R, Punzi L, Borghi C.
Eur Rev Med Pharmacol Sci. 2014 May;18(9):1295-306.
55) The cold-adapted γ-glutamyl-cysteine ligase from the psychrophile Pseudoalteromonas haloplanktis.
Albino A, De Angelis A, Marco S, Severino V, Chambery A, Di Maro A, Desiderio D, Raimo G, Masullo M, De Vendittis E.
Biochimie. 2014 May 23. pii: S0300-9084(14)00134-5. doi: 10.1016/j.biochi.2014.05.003. [Epub ahead of print]
54) Hydration in contrast-induced acute kidney injury.
Briguori C, Condorelli G.
Lancet. 2014 May 24;383(9931):1786-8. doi: 10.1016/S0140-6736(14)60753-4. No abstract available.
53) HMGA1 silencing restores normal stem cell characteristics in colon cancer stem cells by increasing p53 levels.
Puca F, Colamaio M, Federico A, Gemei M, Tosti N, Bastos AU, Del Vecchio L, Pece S, Battista S,Fusco A.
Oncotarget. 2014 Apr 18. [Epub ahead of print]
52) Mta2 promotes Tipin-dependent maintenance of replication fork integrity.
Errico A, Aze A, Costanzo V.
Cell Cycle. 2014 May 15;13(13). [Epub ahead of print]
51) Exploitation of a Very Small Peptide Nucleic Acid as a New Inhibit or of miR-509-3p Involved in the Regulation of Cystic Fibrosis Disease-Gene Expression.
Amato F, Tomaiuolo R, Nici F, Borbone N, Elce A, Catalanotti B, D’Errico S, Morgillo CM, De Rosa G, Mayol L, Piccialli G, Oliviero G, Castaldo G.
Biomed Res Int. 2014;2014:610718. doi: 10.1155/2014/610718. Epub 2014 Apr 15.
50) The dual PI3K/mTOR inhibitor PKI-587 enhances sensitivity to cetuximab in EGFR-resistant human head and neck cancer models.
D’Amato V, Rosa R, D’Amato C, Formisano L, Marciano R, Nappi L, Raimondo L, Di Mauro C, Servetto A, Fusciello C, Veneziani BM, De Placido S, Bianco R.
Br J Cancer. 2014 May 13. doi: 10.1038/bjc.2014.241. [Epub ahead of print]
49) Bimodal effect of D-aspartate on brain aging processes: insights from animal models.
Errico F, Di Maio A, Marsili V, Squillace M, Vitucci D, Napolitano F, Usiello A.
J Biol Regul Homeost Agents. 2013 Apr-Jun;27(2 Suppl):49-59.
48) The Anti-Proliferative Effect of L-Carnosine Correlates with a Decreased Expression of Hypoxia Inducible Factor 1 alpha in Human Colon Cancer Cells.
Iovine B, Oliviero G, Garofalo M, Orefice M, Nocella F, Borbone N, Piccialli V, Centore R, Mazzone M, Piccialli G, Bevilacqua MA.
PLoS One. 2014 May 7;9(5):e96755. doi: 10.1371/journal.pone.0096755. eCollection 2014.
47) Hmga1/Hmga2 double knock-out mice display a “superpygmy” phenotype.
Federico A, Forzati F, Esposito F, Arra C, Palma G, Barbieri A, Palmieri D, Fedele M, Pierantoni GM, De Martino I, Fusco A.
Biol Open. 2014 Apr 11. pii: bio.20146759v1. doi: 10.1242/bio.20146759. [Epub ahead of print]
46) Successful anti-SR-BI mAb therapy in humanized mice after challenge with HCV variants with in vitro resistance to SR-BI-targeting agents.
Vercauteren K, Van Den Eede N, Mesalam AA, Belouzard S, Catanese MT, Bankwitz D, Wong-Staal F, Cortese R, Dubuisson J, Rice CM, Pietschmann T, Leroux-Roels G, Nicosia A, Meuleman P.
Hepatology. 2014 May 3. doi: 10.1002/hep.27196. [Epub ahead of print]
45) Loss of β-catenin triggers oxidative stress and impairs hematopoietic regeneration.
Lento W, Ito T, Zhao C, Harris JR, Huang W, Jiang C, Owzar K, Piryani S, Racioppi L, Chao N, Reya T.
Genes Dev. 2014 May 1;28(9):995-1004. doi: 10.1101/gad.231944.113.
44) Crucial role of androgen receptor in vascular H2S biosynthesis induced by testosterone.
Brancaleone V, Vellecco V, Matassa D, d’Emmanuele di Villa Bianca R, Sorrentino R, Ianaro A, Bucci M, Esposito F, Cirino
G. Br J Pharmacol. 2014 Apr 21. doi: 10.1111/bph.12740. [Epub ahead of print]
43) Cross talk between the bombesin neuropeptide receptor and Sonic hedgehog pathways in small cell lung carcinoma.
Castellone MD, Laukkanen MO, Teramoto H, Bellelli R, Alì G, Fontanini G, Santoro M, Gutkind JS.
Oncogene. 2014 Apr 21. doi: 10.1038/onc.2014.104. [Epub ahead of print]
42) Tirofiban induces VEGF production and stimulates migration and proliferation of endothelial cells.
Giordano A, D’Angelillo A, Romano S, D’Arrigo P, Corcione N, Bisogni R, Messina S, Polimeno M, Pepino P, Ferraro P, Romano MF.
Vascul Pharmacol. 2014 Apr 18. pii: S1537-1891(14)00074-3. doi: 10.1016/j.vph.2014.04.002. [Epub ahead of print]
41) TRAP1 role in endoplasmic reticulum stress protection favors resistance to anthracyclins in breast carcinoma cells.
Sisinni L, Maddalena F, Lettini G, Condelli V, Matassa DS, Esposito F, Landriscina M.
Int J Oncol. 2014 Feb;44(2):573-82. doi: 10.3892/ijo.2013.2199. Epub 2013 Nov 29.
40) Combinations of genetic data in a study of neuroblastoma risk genotypes.
Capasso M, Calabrese FM, Iolascon A, Mellerup E.
Cancer Genet. 2014 Feb 15. pii: S2210-7762(14)00037-4. doi: 10.1016/j.cancergen.2014.02.004. [Epub ahead of print]
39) A De Novo Designed Library of Linear Helical Peptides: An Exploratory Tool in the Discovery of Protein-Protein Interaction Modulators.
Bonache MA, Balsera B, López-Méndez B, Millet O, Brancaccio D, Gomez-Monterrey I, Carotenuto A,Pavone LM, Reille-Seroussi M, Gagey-Eilstein N, Vidal M, de la Torre R, Fernandez-Carvajal A, Ferrer-Montiel A, Garcia-Lopez MT, Martín-Martínez M, Perez de Vega MJ, Gonzalez-Muniz R.
ACS Comb Sci. 2014 Apr 11. [Epub ahead of print]
38) Successful hematopoietic stem cell transplantation in a patient with congenital dyserythropoietic anemia type II.
Unal S, Russo R, Gumruk F, Kuskonmaz B, Cetin M, Sayli T, Tavil B, Langella C, Iolascon A, Uckan Cetinkaya D.
Pediatr Transplant. 2014 Apr 12. doi: 10.1111/petr.12254. [Epub ahead of print]
37) NRIP1/RIP140 siRNA-mediated attenuation counteracts mitochondrial dysfunction in down syndrome.
Izzo A, Manco R, Bonfiglio F, Calì G, de Cristofaro T, Patergnani S, Cicatiello R, Scrima R, Zannini M, Pinton P, Conti A, Nitsch L.
Hum Mol Genet. 2014 Apr 3. [Epub ahead of print]
36) Role of Noncoding RNAs in the Regulation of P-TEFb Availability and Enzymatic Activity.
Napolitano G, Lania L, Majello B.
Biomed Res Int. 2014;2014:643805. Epub 2014 Feb 19. Review.
35) Golgi sorting regulates organization and activity of GPI proteins at apical membranes.
Paladino S, Lebreton S, Tivodar S, Formiggini F, Ossato G, Gratton E, Tramier M, Coppey-Moisan M, Zurzolo C.
Nat Chem Biol. 2014 Mar 30. doi: 10.1038/nchembio.1495. [Epub ahead of print]
34) miR-23b and miR-130b expression is downregulated in pituitary adenomas.
Leone V, Langella C, D’Angelo D, Mussnich P, Wierinckx A, Terracciano L, Raverot G, Lachuer J, Rotondi S, Jaffrain-Rea ML, Trouillas J, Fusco A.
Mol Cell Endocrinol. 2014 Mar 27. pii: S0303-7207(14)00084-7. doi: 10.1016/j.mce.2014.03.002. [Epub ahead of print]
33) MK-5172 : a second-generation protease inhibitor for the treatment of hepatitis C virus infection.
Gentile I, Buonomo AR, Borgia F, Zappulo E, Castaldo G, Borgia G.
Expert Opin Investig Drugs. 2014 Mar 26. [Epub ahead of print]
32) Rare Variants in TP53 and Susceptibility to Neuroblastoma.
Diskin SJ, Capasso M, Diamond M, Oldridge DA, Conkrite K, Bosse KR, Russell MR, Iolascon A, Hakonarson H, Devoto M, Maris JM.
J Natl Cancer Inst. 2014 Mar 14. [Epub ahead of print]
31) Autophagygenesvariants and paediatricCrohn’sdiseasephenotype: A single-centre experience.
Strisciuglio C, Auricchio R, Martinelli M, Staiano A, Giugliano FP, Andreozzi M, De Rosa M, Giannetti E, Gianfrani C, Izzo P, Troncone R, Miele E.
Dig Liver Dis. 2014 Mar 19. pii: S1590-8658(14)00250-3. doi: 10.1016/j.dld.2014.02.016. [Epubahead of print]
30) Typing of Ochrobactrumanthropi clinical isolates using automated repetitive extragenic palindromic-polymerase chainreaction DNA fingerprinting and matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry.
Quirino A, Pulcrano G, Rametti L, Puccio R, Marascio N, Catania MR, Matera G, Liberto MC, Focà A.
BMC Microbiol. 2014 Mar 22;14(1):74. [Epub ahead of print]
29) Isoflavones in aglycone solution enhance ultraviolet B-induced DNA damage repair efficiency.
Iovine B, Garofalo M, Orefice M, Giannini V, Gasparri F, Monfrecola G, Bevilacqua MA.
Clin Exp Dermatol. 2014 Apr;39(3):391-4. doi: 10.1111/ced.12290.
28) Evaluation of cytotoxic effects of 7-dehydrocholesterol on melanoma cells.
Gelzo M, Granato G, Albano F, Arcucci A, Dello Russo A, De Vendittis E, Ruocco MR, Corso G.
Free Radic Biol Med. 2014 Feb 20. pii: S0891-5849(14)00090-2. doi: 10.1016/j.freeradbiomed.2014.02.013. [Epub ahead of print]
27)Adenovirus type 4 and type 7 vaccination or type 4 respiratory infection elicit minimal cross-reactive antibody to non-human adenovirus vaccine vectors.
Paris R, Kuschner RA, Binn L, Thomas SJ, Colloca S, Nicosia A, Cortese R, Bailer RT, Sullivan N, Koup RA.
Clin Vaccine Immunol. 2014 Mar 12. [Epub ahead of print]
26) The novel variant p.Ser465Leu in the PCSK9 gene does not account for the decreased LDLR activity in members of a FH family.
Ruotolo A, Di Taranto MD, D’Agostino MN, Marotta G, Gentile M, Nunziata M, Sodano M, Di Noto R,Del Vecchio L, Rubba P, Fortunato G.
ClinChem Lab Med. 2014 Mar 6. pii: /j/cclm-ahead-of-print/cclm-2014-0144/cclm-2014-0144.xml. doi: 10.1515/cclm-2014-0144. [Epub ahead of print] No abstract available.
25) Glix 13, a New Drug Acting on Glutamatergic Pathways in Children and Animal Models of Autism Spectrum Disorders.
Santini AC, Pierantoni GM, Gerlini R, Iorio R, Olabinjo Y, Giovane A, Di Domenico M, Sogos C.
Biomed Res Int. 2014;2014:234295. Epub 2014 Jan 30. Review.
24) Combined adenovirus vector and hepatitis C virus envelope protein prime-boost regime elicits T cell and neutralizing antibody immune responses.
Chmielewska AM, Naddeo M, Capone S, Ammendola V, Hu K, Meredith L, Verhoye L, Rychlowska M, Rappuoli R, Ulmer JB, Colloca S, Nicosia A, Cortese R, Leroux-Roels G, Balfe P, Bienkowska-Szewczyk K, Meuleman P, McKeating JA, Folgori A.
J Virol. 2014 Mar 5. [Epub ahead of print]
23) Ledipasvir : a novel synthetic antiviral for the treatment of HCV infection.
Gentile I, Buonomo AR, Borgia F, Castaldo G, Borgia G.
Expert OpinInvestig Drugs. 2014 Apr;23(4):561-71. doi: 10.1517/13543784.2014.892581. Epub 2014 Mar 4.
22) Tropheryma whipplei, the Agent of Whipple’s Disease, Affects the Early to Late Phagosome Transition and Survives in a Rab5- and Rab7-Positive Compartment.
Mottola G, Boucherit N, Trouplin V, Oury Barry A, Soubeyran P, Mege JL, Ghigo E.
PLoS One. 2014 Feb 24;9(2):e89367. doi: 10.1371/journal.pone.0089367. eCollection 2014.
21) Inhibition of Receptor Signaling and of Glioblastoma-derived Tumor Growth by a Novel PDGFRβ Aptamer.
Camorani S, Esposito CL, Rienzo A, Catuogno S, Iaboni M, Condorelli G, de Franciscis V, Cerchia L.
Mol Ther. 2014 Jan 2. doi: 10.1038/mt.2013.300. [Epub ahead of print]
20) ATM controls proper mitotic spindle structure.
Palazzo L, Della Monica R, Visconti R, Costanzo V, Grieco D.
Cell Cycle. 2014 Feb 6;13(7). [Epub ahead of print]
19) Prediction of acute pancreatitis risk based on PIP score in children with cystic fibrosis.
Terlizzi V, Tosco A, Tomaiuolo R, Sepe A, Amato N, Casale A, Mercogliano C, De Gregorio F, Improta F, Elce A, Castaldo G, Raia V.
J Cyst Fibros. 2014 Feb 10. pii: S1569-1993(14)00030-7. doi: 10.1016/j.jcf.2014.01.007. [Epub ahead of print]
18) Ranolazine protects from doxorubicin-induced oxidative stress and cardiac dysfunction.
Tocchetti CG, Carpi A, Coppola C, Quintavalle C, Rea D, Campesan M, Arcari A, Piscopo G, Cipresso C, Monti MG, De Lorenzo C, Arra C, Condorelli G, Di Lisa F, Maurea N.
Eur J Heart Fail. 2014 Jan 6. doi: 10.1002/ejhf.50. [Epub ahead of print]
17) INDOLEAMINE 2,3-DIOXYGENASE 1 (IDO1) IS UPREGULATED IN THYROID CARCINOMA AND DRIVES THE DEVELOPMENT OF AN IMMUNOSUPPRESSANT TUMOR MICROENVIRONMENT.
Moretti S, Menicali E, Voce P, Morelli S, Cantarelli S, Sponziello M, Colella R, Fallarino F, Orabona C, Alunno A, de Biase D, Bini V, Mameli MG, Filetti S, Gerli R, Macchiarulo A, Melillo RM, Tallini G,Santoro M, Puccetti P, Avenia N, Puxeddu E.
J Clin Endocrinol Metab. 2014 Feb 11:jc20133351. [Epub ahead of print]
16) Cytogenetic Prognostication Within Medulloblastoma Subgroups.
Shih DJ, Northcott PA, Remke M, Korshunov A, Ramaswamy V, Kool M, Luu B, Yao Y, Wang X, Dubuc AM, Garzia L, Peacock J, Mack SC, Wu X, Rolider A, Morrissy AS, Cavalli FM, Jones DT, Zitterbart K, Faria CC, Schüller U, Kren L, Kumabe T, Tominaga T, Shin Ra Y, Garami M, Hauser P, Chan JA, Robinson S, Bognár L, Klekner A, Saad AG, Liau LM, Albrecht S, Fontebasso A, Cinalli G, De Antonellis P, Zollo M, Cooper MK, Thompson RC, Bailey S, Lindsey JC, Di Rocco C, Massimi L, Michiels EM, Scherer SW, Phillips JJ, Gupta N, Fan X, Muraszko KM, Vibhakar R, Eberhart CG, Fouladi M, Lach B, Jung S, Wechsler-Reya RJ, Fèvre-Montange M, Jouvet A, Jabado N, Pollack IF, Weiss WA, Lee JY, Cho BK, Kim SK, Wang KC, Leonard JR, Rubin JB, de Torres C, Lavarino C, Mora J, Cho YJ, Tabori U, Olson JM, Gajjar A, Packer RJ, Rutkowski S, Pomeroy SL, French PJ, Kloosterhof NK, Kros JM, Van Meir EG, Clifford SC, Bourdeaut F, Delattre O, Doz FF, Hawkins CE, Malkin D, Grajkowska WA, Perek-Polnik M, Bouffet E, Rutka JT, Pfister SM, Taylor MD.
J Clin Oncol. 2014 Feb 3. [Epub ahead of print]
15) Should a BRCA2 stop codon human variant, usually considered a polymorphism, be classified as a predisposing mutation?
D’Argenio V, Esposito MV, Gilder JA, Frisso G, Salvatore F.
Cancer. 2014 Feb 5. doi: 10.1002/cncr.28605. [Epub ahead of print] No abstract available.
14) Peptide inhibitors of C3 activation as a novel strategy of complement inhibition for the treatment of paroxysmal nocturnal hemoglobinuria.
Risitano AM, Ricklin D, Huang Y, Reis ES, Chen H, Ricci P, Lin Z, Pascariello C, Raia M, Sica M, Del Vecchio L, Pane F, Lupu F, Notaro R, Resuello RR, Deangelis RA, Lambris JD.
Blood. 2014 Feb 4. [Epub ahead of print]
13) Fusion of HCV non-structural antigen to MHC Class II associated invariant chain enhances T cell responses induced by vectored vaccines in non-human primates.
Capone S, Naddeo M, D’Alise AM, Abbate A, Grazioli F, Del Gaudio A, Del Sorbo M, Esposito ML, Ammendola V, Perretta G, Taglioni A, Colloca S, Nicosia A, Cortese R, Folgori A.
Mol Ther. 2014 Jan 30. doi: 10.1038/mt.2014.15. [Epub ahead of print]
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12) Molecular Analysis of Cluster Headache.
Zarrilli F, Tomaiuolo R, Ceglia C, Lombardo B, Izzo B, Castaldo G, Pastore L, Simone RD.
Clin J Pain. 2014 Jan 24. [Epub ahead of print]
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11) FKBP51 increases the tumour-promoter potential of TGF-beta.
Romano S, D Angelillo A, D Arrigo P, Staibano S, Greco A, Brunetti A, Scalvenzi M, Bisogni R, Scala I, Romano MF.
Clin Transl Med. 2014 Jan 27;3(1):1. [Epub ahead of print]
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10) Loeys-Dietz syndrome type 4, caused by chromothripsis, involving the TGFB2 gene.
Fontana P, Genesio R, Casertano A, Cappuccio G, Mormile A, Nitsch L, Iolascon A, Andria G, Melis D.
Gene. 2014 Jan 15. pii: S0378-1119(14)00038-9. doi: 10.1016/j.gene.2014.01.017. [Epub ahead of print]
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9) Hematopoietic Stem/Progenitor cells express myoglobin and neuroglobin: Adaptation to hypoxia or prevention from oxidative stress?
D’Aprile A, Scrima R, Quarato G, Tataranni T, Falzetti F, Di Ianni M, Gemei M, Del Vecchio L, Piccoli C, Capitanio N.
Stem Cells. 2014 Jan 20. doi: 10.1002/stem.1646. [Epub ahead of print]
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8) Multifunctional aptamer-miRNA conjugates for targeted cancer therapy.
Esposito CL1, Cerchia L1, Catuogno S1, de Vita G1, Dassie JP2, Santamaria G3, Swiderski P4, Condorelli G1,5, Giangrande PH2,6 and de Franciscis V1
Mol Ther. 2014 Jan 20. doi: 10.1038/mt.2014.5. [Epub ahead of print]
7) Structural and denaturation studies of two mutants of a cold adapted superoxide dismutase point to the importance of electrostatic interactions in protein stability.
Merlino A, Krauss IR, Castellano I, Ruocco MR, Capasso A, De Vendittis E, Rossi B, Sica F.
Biochim Biophys Acta. 2014 Jan 16. pii: S1570-9639(14)00010-7. doi: 10.1016/j.bbapap.2014.01.007. [Epub ahead of print]
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6) Effects of a second-generation human anti-ErbB2 ImmunoRNase on trastuzumab-resistant tumors and cardiac cells.
D’Avino C, Paciello R, Riccio G, Coppola M, Laccetti P, Maurea N, Raines RT, De Lorenzo C.
Protein Eng Des Sel. 2014 Jan 12. [Epub ahead of print]
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5) Update: The Status of Clinical Trials of Kinase Inhibitors in Thyroid Cancer.
Wells SA Jr, Santoro M.
J Clin Endocrinol Metab. 2014 Jan 13:jc20132622. [Epub ahead of print]
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4) Celiac anti-type 2 transglutaminase antibodies induce phosphoproteome modification in intestinal epithelial caco-2 cells.
Paolella G, Caputo I, Marabotti A, Lepretti M, Salzano AM, Scaloni A, Vitale M, Zambrano N, Sblattero D, Esposito C.
PLoS One. 2013 Dec 31;8(12):e84403. doi: 10.1371/journal.pone.0084403.
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3) Novel Pancreas Organogenesis Markers Refine the Pancreatic Differentiation Roadmap of Embryonic Stem cells.
De Angelis MT, Russo F, D’Angelo F, Federico A, Gemei M, Del Vecchio L, Ceccarelli M, De Felice M, Falco G.
Stem Cell Rev. 2014 Jan 5. [Epub ahead of print]
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2) Identification of a Novel Gene Signature of ES Cells Self-Renewal Fluctuation through System-Wide Analysis.
Cerulo L, Tagliaferri D, Marotta P, Zoppoli P, Russo F, Mazio C, De Felice M, Ceccarelli M, Falco G.
PLoS One. 2014 Jan 2;9(1):e83235. doi: 10.1371/journal.pone.0083235.
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1) Child Neurology: Recurrent rhabdomyolysis due to a fatty acid oxidation disorder.
Terrone G, Ruoppolo M, Brunetti-Pierri N, Cozzolino C, Scolamiero E, Parenti G, Romano A, Andria G, Salvatore F, Frisso G.
Neurology. 2014 Jan 7;82(1):e1-4. doi: 10.1212/01.wnl.0000438217.31437.72.
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