PhD Program in Molecular Medicine and Medical Biotechnology Cycle 39
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Description
PhD Program in Molecular Medicine and Medical Biotechnology
- Description
Vision and didactic activities
This doctoral program is specifically designed to train researchers who wish to develop their careers in basic and translational research in biomedicine. This aim is pursued through an intense training of experimental research in the laboratory, of an interdisciplinary, multidisciplinary and transdisciplinary type, in subjects pertaining to biochemistry, cellular and molecular biology, microbiology, molecular diagnostics, innovative therapies, models of human diseases and computational biology. Understanding human diseases at the molecular level is the main objective of the training and experimental work that will be undertaken by PhD students also considering the possible effects in terms of intellectual property and industrial implications of research. In this context, the doctoral program is consistent with the Strategic plan of the University
As far as the services available to doctoral students, the Department provides numerous state-of-the-art equipped laboratories for cell culture, molecular biology and biochemistry. In addition, it set up three main core facilities for next generation nucleic acid sequencing, imaging, and flow cytometry. The NGS platform is equipped with the automatic nucleic acid extractor, Nanophotometer and Qubit 4 for their quantization, TapeStation for quality control, and finally the NextSeq550 sequencer. The platform also has a microfluidic system for performing single cell RNAseq. The cell imaging platform is equipped with several state-of-the-art fluorescence microscopy systems that ensure high-resolution and high-contrast analysis of fixed or in vivo biological samples (cells, tissues and model organisms), such as a scanning confocal microscope laser equipped with 4 laser lines (for excitations from ultraviolet to far red), with high performance objectives (from 10x to 100x), and 2 highly sensitive detectors; the ApoTome.2 system based on structured lighting technology; the Thunder system based on opto-digital technology. The cytofluorimetry platform includes a latest generation continuous flow cytometer that allows multiparametric analysis equipped with 3 Blue, Red and Violet lasers, capable of detecting up to 14 parameters simultaneously and a bench flow cytometer equipped with three lasers (488 nm, 640 nm and 405 nm) and 10 optical channels and software for automated cell analysis.
Board of Teachers
The Academic Board is made up of professors from the "Federico II" University affiliated to the Department of Molecular Medicine and Medical Biotechnology, appointed on the basis of the scientific curriculum, which is available on the individual professor pages in WebDocenti (www.docenti.unina.it).
Student selection
Candidates are young graduates with an excellent education track willing to develop an independent career in biomedical research. Admission to the program is a three-tier process including: CV evaluation, a written essay on the specific areas indicated above and an oral interview to assess basic knowledge, predisposition to biomedical research and motivation. English fluency is also assessed. Once selected, students are assigned by the faculty to a specific supervisor, staff member of the Department, to develop one of the research projects available in the specific year.
Program organization
The supervisor will be responsible for training and research activities. Once a year, the student is expected to give a seminar to peers and supervisors on the results obtained, to allow faculty to decide on admission to the following year. The student can spend up to 18 months in a foreign laboratory.
Training and Monitoring
Students will attend residential courses on the thematic areas of the program organized by members of the faculty and renowned external scientists. The courses include formal lectures and seminars. A special focus of the training is dedicated to the development of skills, such as the ability of presenting results in journal clubs, writing a manuscript and a research proposal, reviewing a research paper, experimental planning, and problem solving. To achieve the Doctorate title, students will submit a Dissertation in English and publicly present their data (PhD viva) to an external Committee.
Fellowships
Several 3 years fellowships is available as published in the Application call each year.
For information:
Dr Nausicaa Zendrini (dottorato_mmbm@unina.it)
Open Day PhD program
Schedule (not available yet)
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Cycle:
XXXIX -
Board committee:
- Board committee:
Board of teachers
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Organization of courses and educational activities:
- Admission test:
CV qualification + Written test + Oral examination
- Admissions exam topics:
The admission test (oral and written, when planned) will focus on general topics concerning basic biochemical, biological, and genetic mechanisms and the pathological basis of diseases
Suggested readings for the Admission exam
Molecular Biology of the Cell
Bruce Alberts, Rebecca Heald, Alexander D. Johnson, David Morgan, Martin Raff
Lehninger Principles of Biochemistry
David L. Nelson, Michael M. Cox
Robbins & Cotran - Pathologic Basis of Disease
Vinay Kumar, Abul Abbas, Jon Aster
- Available positions:
See PhD call
- Course length: 3 years
- Requirements:
See PhD call
- Notes:
Research lines (see)
- Contacts:
Dr Nausicaa Zendrini (dottorato_mmbm@unina.it)
- Candidatures deadline: (not available yet)
- Test calendar:
See PhD call
1) Assessment of the CV qualification:
2) Written text:
3) Oral exam:
Results (not available yet)
Final Results
(not available yet)